- Title
- Comprehensive data on the mechanical properties and biodegradation profile of polylactide composites developed for hard tissue repairs
- Creator
- Aworinde, Abraham K
- Creator
- Adeosun, Samson O
- Creator
- Oyawale, Festus A
- Creator
- Emagbetere, Eyere
- Creator
- Ishola, Felix A
- Creator
- Olatunji, Obafemi
- Creator
- Akinlab, Stephen
- Creator
- Oyedepo, Sunday O
- Creator
- Ajayi, Oluseyi O
- Creator
- Akinlabi, Esther T
- Description
- Africa, the ancestral home of all modern humans, is the most informative continent for understanding the human genome and its contribution to complex disease. To better understand the genetics of schizophrenia, we studied the illness in the Xhosa population of South Africa, recruiting 909 cases and 917 age-, gender-, and residence-matched controls. Individuals with schizophrenia were significantly more likely than controls to harbor private, severely damaging mutations in genes that are critical to synaptic function, including neural circuitry mediated by the neurotransmitters glutamine, γ-aminobutyric acid, and dopamine. Schizophrenia is genetically highly heterogeneous, involving severe ultrarare mutations in genes that are critical to synaptic plasticity. The depth of genetic variation in Africa revealed this relationship with a moderate sample size and informed our understanding of the genetics of schizophrenia worldwide.
- Date
- 2020
- Subject
- Regeneration (Biology)
- Subject
- Vickers microhardness
- Subject
- Melt-blending technique
- Type
- text, article
- Identifier
- http://hdl.handle.net/11260/3149
- Identifier
- vital:43158
- Identifier
- https://doi.org/10.1016/j.dib.2020.106107
- Format
- computer, online resource, application/pdf, 1 online resource (9 pages), pdf
- Language
- English
- Relation
- Data in Brief, Abraham K. Aworinde, Samson O. Adeosun, Festus A. Oyawale, Eyere Emagbetere, Felix A. Ishola, Obafemi Olatunji, Stephen A. Akinlabi, Sunday O. Oyedepo, Oluseyi O. Ajayi, Esther T. Akinlabi,Comprehensive data on the mechanical properties and biodegradation profile of polylactide composites developed for hard tissue repairs, Data in Brief, Volume 32,2020, 106107. https://doi.org/10.1016/j.dib.2020.106107., Data in Brief volume 32 number 106107 2020
- Rights
- © The Author/s, Published by Elsevier Inc. This is an open access article under the CCBY license. http://creativecommons.org/licenses/by/4.0/, Open Access
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