- Title
- Determination of Carbapenemases and Colistin Resistance in the Clinical Isolates from Healthcare Facilities in Mthatha and Surrounding Areas
- Creator
- Ndlela, Silindokuhle
- Description
- Antimicrobial resistance is associated with the emergence of 3 carbapenemase enzymes that hydrolyze carbapenem antibiotics. These enzymes 4 are carried by certain carbapenemase-producing genes. The emergence of 5 carbapenem resistant Enterobacterales (CRE) has become a serious public health 6 threat in South Africa and globally, and has led to the use of colistin for treating 7 severe infections. The aim of the study is to determine the prevalence of 8 carbapenemase-producing genes, the minimum inhibitory concentration (MIC) for 9 the antibiotic colistin, and the prevalence of the mobile colistin resistant gene mcr 10 1 in clinical isolates drawn from healthcare facilities in Mthatha and surrounding 11 areas…
- Description
- Degree: M. Science (Medical Microbiology)
- Date
- 2025
- Subject
- Antimicrobial resistance
- Subject
- Healthcare facilities
- Subject
- Clinical Isolates
- Subject
- Mthatha
- Type
- Masters (Thesis)
- Identifier
- http://hdl.handle.net/11260/13473
- Identifier
- vital:78935
- Language
- English
- Rights
- Walter Sisulu University
- Hits: 6
- Visitors: 4
- Downloads: 2
| Thumbnail | File | Description | Size | Format | |||
|---|---|---|---|---|---|---|---|
| View Details Download | SOURCE1 | Ndlela, S. Masters Thesis.pdf | 2 MB | Adobe Acrobat PDF | View Details Download |