- Title
- Omics-based molecular techniques in oral pathology centred cancer: prospect and challenges in Africa
- Creator
- Adeola, Henry A.
- Creator
- Soyele, Olujide.O.
- Creator
- Adefuye, Anthonio O.
- Creator
- Jimoh, Sikiru A.
- Creator
- Butali, Azeez
- Description
- Background:The completion of the human genome project and the accomplished milestones in the human proteome project; as well as the progress made so far in computational bioinformatics and “big data” processing have contributed immensely to individualized/personalized medicine in the developed world.Main body:At the dawn of precision medicine, various omics-based therapies and bioengineering can now be applied accurately for the diagnosis, prognosis, treatment, and risk stratification of cancer in a manner that was hitherto not thought possible. The widespread introduction of genomics and other omics-based approaches into the postgraduate training curriculum of diverse medical and dental specialties, including pathology has improved the proficiency of practitioners in the use of novel molecular signatures in patient management. In addition, intricate details about disease disparity among different human populations are beginning to emerge. This would facilitate the use of tailor-made novel theranostic methods based on emerging molecular evidences.Conclusion:In this review, we examined the challenges and prospects of using currently available omics-based technologies vis-à-vis oral pathology as well as prompt cancer diagnosis and treatment in a resource limited setting.Keywords:Omics-based, Molecular, Developing world, Oral pathology, Challenges
- Date
- 2017
- Subject
- Eastern Cape, South Africa Oral mucosa--Cancer Oral Pathology Cancer Computer File
- Type
- text, article
- Identifier
- http://hdl.handle.net/11260/5857
- Identifier
- vital:44658
- Identifier
- https://DOI10.1186/s12935-017-0432-8
- Format
- 12 pages, pdf
- Publisher
- Biomed Central
- Language
- English
- Relation
- Cancer Cell International, Adeola et al. Cancer Cell Int (2017) 17:61 DOI 10.1186/s12935-017-0432-8, Cancer Cell International volume 17 number 61 1 12 2017
- Rights
- © Adeola et al. 2017, This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
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