- Title
- Atypical HIV-vacuolar myelopathy: a case report :
- Creator
- Mongezi, Tau
- Creator
- Sibi, Joseph
- Creator
- Jerry, George
- Creator
- Lourdes de Fátima, Ibañez Valdés
- Creator
- Tozama, Dubula
- Creator
- Humberto, Foyaca Sibat
- Description
- Background: Here, we report an atypical HIV-vacuolar myelopathy and search the available medical literature about atypical presentations of human immunodefciency virus associate vacuolar myelopathy (HIV-VM) and immunoglobu‑ lin therapy response. Case: A 26-year-old lady who was 4 weeks postpartum presented to us with acute faccid quadriparesis, with no sen‑ sory level. Extensive workup ruled out other causes of myelopathy. She developed a stage 3 acute kidney injury, and MRI showed difuse cord atrophy involving the lower cervical and thoracic cord. The patient received IV-immunoglob‑ ulin, ARVs, and supportive therapy with inadequate response. Unfortunately, she developed nosocomial pneumonia and died. Discussion: In HIV-VM, there is spinal cord atrophy, which mainly involves the thoracic cord. In our case, this patho‑ logical process also afected the spinal cord’s cervical region, leading to faccid tetraplegia, with high CD4 level, with‑ out response to the treatment, including intravenous immunoglobulin. Keynotes: Vacuolar myelopathy, HIV, Immunoglobulin therapy, faccid tetraplegia, hypokalaemia. Renal failure. Keywords: Human immunodefciency virus, Associated lesions of the nervous system, Human immunodefciency virus-associated myelopathy, Intravenous immunoglobulin administration, Case report, HIV-vacuolar myelopathy
- Date
- 2021-06
- Subject
- South Africa HIV (Viruses) Cervical spondylotic myelopathy Article
- Type
- text, article
- Identifier
- http://hdl.handle.net/11260/7670
- Identifier
- vital:54741
- Identifier
- https://doi.org/10.1186/s40001-021-00483-0
- Format
- 6 pages, pdf
- Publisher
- Adonis and Abbey Publishers Ltd
- Language
- English
- Relation
- BMC (Springer Nature), Mongezi et al (2021). Atypical HIV-vacuolar myelopathy: a case report. Eur J Med Res (2021) 26:13 https://doi.org/10.1186/s40001-021-00483-0, BMC (Springer Nature) volume 26 Issue 13 1 6 2021
- Rights
- © The Author(s). 2021, This article is licensed under a Creative Commons Attribution 4.0 International License
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