The effects of Human-Wildlife Conflict (HWC) on mental health: the case of Shezongo Community of Kafue National Park (KNP), Zambia
- Authors: Smith, Loryn Janine
- Date: 2024-10-11
- Subjects: Uncatalogued
- Language: English
- Type: Academic theses , Master's theses , text
- Identifier: http://hdl.handle.net/10962/465843 , vital:76658
- Description: Background: Human-wildlife conflict (HWC) is a bi-directional relationship affecting man and wild animals. Both species suffer extreme consequences, including encroachment of man into wildlife habitats and the destruction of crops and livestock by wildlife foraging for food sources. HWC is particularly prominent in Game Management Areas (GMAs), situated as buffer zones around national parks. Subsequent conflict between man and wildlife leads to not only physical harm but also psychological distress, exacerbating the consequences for mental health. Objectives: A mixed methods design was used to investigate the effects of HWC on mental health. The study aimed to determine the hidden nature of HWC within a population residing in a GMA region in Kafue National Park, Zambia. Methods: Forty-two participants took part in this study, representing a diverse range of demographic characteristics. Of these, 40 participants completed quantitative measures investigating the effect of HWC on mental health. Additionally, eight participants participated in interviews on the nature of mental health in the context of HWC. Some interview participants also completed the quantitative measures, while others did not. Thematic analysis guided qualitative investigations, while Chi-Square Analyses and Fisher’s Exact Test were used to investigate the association between HWC and mental health. Results and Conclusions: The study found an association between HWC and heightened psychological distress in rural communities residing in GMA areas. Further research is required to improve the symbiotic relationship between man and wildlife, considering the consequences of HWC on human well-being and mental health. , Thesis (MA) -- Faculty of Humanities, Psychology, 2024
- Full Text:
- Date Issued: 2024-10-11
- Authors: Smith, Loryn Janine
- Date: 2024-10-11
- Subjects: Uncatalogued
- Language: English
- Type: Academic theses , Master's theses , text
- Identifier: http://hdl.handle.net/10962/465843 , vital:76658
- Description: Background: Human-wildlife conflict (HWC) is a bi-directional relationship affecting man and wild animals. Both species suffer extreme consequences, including encroachment of man into wildlife habitats and the destruction of crops and livestock by wildlife foraging for food sources. HWC is particularly prominent in Game Management Areas (GMAs), situated as buffer zones around national parks. Subsequent conflict between man and wildlife leads to not only physical harm but also psychological distress, exacerbating the consequences for mental health. Objectives: A mixed methods design was used to investigate the effects of HWC on mental health. The study aimed to determine the hidden nature of HWC within a population residing in a GMA region in Kafue National Park, Zambia. Methods: Forty-two participants took part in this study, representing a diverse range of demographic characteristics. Of these, 40 participants completed quantitative measures investigating the effect of HWC on mental health. Additionally, eight participants participated in interviews on the nature of mental health in the context of HWC. Some interview participants also completed the quantitative measures, while others did not. Thematic analysis guided qualitative investigations, while Chi-Square Analyses and Fisher’s Exact Test were used to investigate the association between HWC and mental health. Results and Conclusions: The study found an association between HWC and heightened psychological distress in rural communities residing in GMA areas. Further research is required to improve the symbiotic relationship between man and wildlife, considering the consequences of HWC on human well-being and mental health. , Thesis (MA) -- Faculty of Humanities, Psychology, 2024
- Full Text:
- Date Issued: 2024-10-11
The use of aeration in constructed wetlands and the potential for earthworm and crop production
- Authors: Cesler, Lia
- Date: 2024-10-11
- Subjects: Constructed wetlands South Africa , Breweries South Africa , Water Purification , Land treatment of wastewater , Sewage Purification Aeration
- Language: English
- Type: Academic theses , Master's theses , text
- Identifier: http://hdl.handle.net/10962/464440 , vital:76511
- Description: Constructed wetlands (CWs) are used in a variety of industries to treat effluent for safe reuse or discharge. They can however take up large areas of land. Adding oxygen can increase treatment efficiency, as it is vital to many nutrient removal pathways, such as nitrification and aerobic respiration. Increasing efficiency can decrease the cost of treatment and reduce land area needed to operate a CW. The study aimed to find the best method of aerating wetlands treating brewery effluent, the potential production of worms and plants in the system and their effects on water treatment. The first experiment tested a hybrid constructed wetland, using small (1.0 m3) ebb and flow filtration additions to a horizontal subsurface flow constructed wetland against nanobubble aeration in a similar horizontal flow wetland cell. It was not possible to add replicates to the study, but findings prompted further investigation into the hybrid setup. Experiment two focussed on the ebb and flow filters within the hybrid system comparing the presence of plants and worms. The ebb and flow filters increased dissolved oxygen (DO) from an average inflow of 3.89 mg/L to an outflow of 5.70 mg/L and decreased the ammonia content of the effluent from 14.8 mg/L to 11.2 mg/L. Swiss chard (Beta vulgaris) was successfully grown in the system and was found not to affect DO. The addition of both Swiss chard and earthworms (Eisenia fetida) was found to decrease PO43- by 17.69 ± 1.36 %. Experiment 3 compared the previous ebb and flow filters to trickle filters with the addition of celery (Apium graveolens) to both systems to determine which filter treated the effluent more effectively. The ebb and flow filters performed better than the trickle filters, increasing the DO by 37.54 ± 0.06 % compared to 19.22 ± 0.06 %. Celery increased this change in both systems, to 44.16 ± 0.06 % in the ebb and flow filters and 30.96 ± 0.06 % in the trickle filters. The ebb and flow filters were also able to decrease the NH3-N concentration by 36.1 ± 0.2 %. This effluent could sustain plant growth; Swiss chard grew at a rate of 0.04 ± 0.02 g/g/d and celery at 0.2 ± 0.1 g/g/d. Ebb and flow filters are better at aerating brewery effluent and decreasing nutrient load than nanobubble pumps and trickle filters. The addition of ebb and flow filters to the CW treating brewery effluent has the potential to improve nutrient removal and provide an edible crop. , Thesis (MSc) -- Faculty of Science, Ichthyology and Fisheries Science, 2024
- Full Text:
- Date Issued: 2024-10-11
- Authors: Cesler, Lia
- Date: 2024-10-11
- Subjects: Constructed wetlands South Africa , Breweries South Africa , Water Purification , Land treatment of wastewater , Sewage Purification Aeration
- Language: English
- Type: Academic theses , Master's theses , text
- Identifier: http://hdl.handle.net/10962/464440 , vital:76511
- Description: Constructed wetlands (CWs) are used in a variety of industries to treat effluent for safe reuse or discharge. They can however take up large areas of land. Adding oxygen can increase treatment efficiency, as it is vital to many nutrient removal pathways, such as nitrification and aerobic respiration. Increasing efficiency can decrease the cost of treatment and reduce land area needed to operate a CW. The study aimed to find the best method of aerating wetlands treating brewery effluent, the potential production of worms and plants in the system and their effects on water treatment. The first experiment tested a hybrid constructed wetland, using small (1.0 m3) ebb and flow filtration additions to a horizontal subsurface flow constructed wetland against nanobubble aeration in a similar horizontal flow wetland cell. It was not possible to add replicates to the study, but findings prompted further investigation into the hybrid setup. Experiment two focussed on the ebb and flow filters within the hybrid system comparing the presence of plants and worms. The ebb and flow filters increased dissolved oxygen (DO) from an average inflow of 3.89 mg/L to an outflow of 5.70 mg/L and decreased the ammonia content of the effluent from 14.8 mg/L to 11.2 mg/L. Swiss chard (Beta vulgaris) was successfully grown in the system and was found not to affect DO. The addition of both Swiss chard and earthworms (Eisenia fetida) was found to decrease PO43- by 17.69 ± 1.36 %. Experiment 3 compared the previous ebb and flow filters to trickle filters with the addition of celery (Apium graveolens) to both systems to determine which filter treated the effluent more effectively. The ebb and flow filters performed better than the trickle filters, increasing the DO by 37.54 ± 0.06 % compared to 19.22 ± 0.06 %. Celery increased this change in both systems, to 44.16 ± 0.06 % in the ebb and flow filters and 30.96 ± 0.06 % in the trickle filters. The ebb and flow filters were also able to decrease the NH3-N concentration by 36.1 ± 0.2 %. This effluent could sustain plant growth; Swiss chard grew at a rate of 0.04 ± 0.02 g/g/d and celery at 0.2 ± 0.1 g/g/d. Ebb and flow filters are better at aerating brewery effluent and decreasing nutrient load than nanobubble pumps and trickle filters. The addition of ebb and flow filters to the CW treating brewery effluent has the potential to improve nutrient removal and provide an edible crop. , Thesis (MSc) -- Faculty of Science, Ichthyology and Fisheries Science, 2024
- Full Text:
- Date Issued: 2024-10-11
A qualitative review on the manner in which psychologists address language barriers in psychological testing with isiXhosa speaking clients
- Authors: Fouche, Nicoleen Leonie
- Date: 2024-04
- Subjects: Language and languages -- Psychological aspects , Psychological tests -- South Africa -- Eastern Cape , Counseling psychology
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10948/63835 , vital:73618
- Description: A racially segregated culture historically influenced the growth of psychological testing and evaluation in South Africa. Thus, South Africa's multicultural and multilingual community poses difficulties for psychologists in their daily work. Most of the psychological tests used by psychologists are predominantly normed in either or only English/Afrikaans. Given the economic and professional resources required to develop new standardised tests for the broader South African population, the current status quo is set to continue for the foreseeable future. Consequently, language barriers pose a challenge when psychometric standardised tests are administered in a language that is different from that of the client, and as a result, psychologists must develop ways to enhance the fairness of these measures for their client base. The avenue of research that was explored is how psychologists overcome the language boundary when assessing clients who speak an indigenous first language, particularly isiXhosa. As such, this study explored this question through qualitative methods. Through purposive sampling, nine psychologists were invited to share their practical expertise on this topic, using semi-structured online interviews. The findings of this study suggested several core themes providing useful methods for other psychologists facing the same challenge, including the challenges with administering psychological tests with isiXhosa clients, the availability of standardised tests in the South African context, and the importance of determining the client’s language proficiency. Five themes with several sub-themes emerged from the study. The study contributes to the currently limited existing body of knowledge, and subsequently to the research area that this study explores - thus further providing guidelines that practitioners can employ when working with clients who are isiXhosa speaking. , Thesis (MA) -- Faculty of Health Science, School of Behavioural & Lifestyle Sciences, 2024
- Full Text:
- Date Issued: 2024-04
- Authors: Fouche, Nicoleen Leonie
- Date: 2024-04
- Subjects: Language and languages -- Psychological aspects , Psychological tests -- South Africa -- Eastern Cape , Counseling psychology
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10948/63835 , vital:73618
- Description: A racially segregated culture historically influenced the growth of psychological testing and evaluation in South Africa. Thus, South Africa's multicultural and multilingual community poses difficulties for psychologists in their daily work. Most of the psychological tests used by psychologists are predominantly normed in either or only English/Afrikaans. Given the economic and professional resources required to develop new standardised tests for the broader South African population, the current status quo is set to continue for the foreseeable future. Consequently, language barriers pose a challenge when psychometric standardised tests are administered in a language that is different from that of the client, and as a result, psychologists must develop ways to enhance the fairness of these measures for their client base. The avenue of research that was explored is how psychologists overcome the language boundary when assessing clients who speak an indigenous first language, particularly isiXhosa. As such, this study explored this question through qualitative methods. Through purposive sampling, nine psychologists were invited to share their practical expertise on this topic, using semi-structured online interviews. The findings of this study suggested several core themes providing useful methods for other psychologists facing the same challenge, including the challenges with administering psychological tests with isiXhosa clients, the availability of standardised tests in the South African context, and the importance of determining the client’s language proficiency. Five themes with several sub-themes emerged from the study. The study contributes to the currently limited existing body of knowledge, and subsequently to the research area that this study explores - thus further providing guidelines that practitioners can employ when working with clients who are isiXhosa speaking. , Thesis (MA) -- Faculty of Health Science, School of Behavioural & Lifestyle Sciences, 2024
- Full Text:
- Date Issued: 2024-04
An evaluation of supply chain stakeholder engagement in terms of customer specific requirements: a case study of an automotive supplier and the pressures around the automotive original equipment manufacturers’ (OEMs’) requirements
- Authors: van Staden, Shelby
- Date: 2024-04
- Subjects: Business logistics , Materials management , Automobile industry and trade -- South Africa
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/${Handle} , vital:74160
- Description: The central aim of this study was to assess the engagement of supply chain stakeholders, namely OEMs and an automotive supplier, in relation to customer-specific requirements. This objective was accomplished by identifying the communication methods employed by both parties for addressing customer-specific needs. Additionally, the study aimed to pinpoint the factors that promoted engagement between OEMs and automotive suppliers concerning these requirements. Conversely, it aimed to uncover the factors that hindered such engagement. Lastly, the research aimed to evaluate whether this engagement effectively alleviated the pressures faced by the automotive supplier regarding customer-specific requirements. The broader goal of the research was to comprehend how supply chain stakeholder engagement operated between OEMs and an automotive supplier with respect to customer-specific requirements. This was pursued through secondary objectives, which entailed examining how communication transpired between OEMs and an automotive supplier, the degree of participatory nature in this communication, the barriers and catalysts influencing customer-specific requirements, and whether this engagement mitigated the pressures borne by the automotive supplier. These objectives were instrumental in revealing opportunities for enhancing OEM communication, thereby positively contributing to their relationships with supply chain partners and mitigating the added burdens they faced. The research followed a qualitative case study design, utilizing semi-structured interviews to delve into the experiences of participants carefully selected from an automotive supplier. These participants were chosen based on their interactions with OEM customers, thereby providing pertinent insights into these interactions. Thematic analysis was employed for data analysis, uncovering codes, categories, and overarching themes from participants’ responses. The findings of the research highlighted certain consistent themes, shedding light on which communication methods were employed more frequently, as well as the rationale behind their usage. Notably, online platforms emerged as a popular channel, and daily communication was preferred. The research also revealed a recurring theme wherein OEMs assumed a controlling role, rather than fostering a mutually advantageous partnership in addressing issues. Additionally, communication barriers were observed in the use of online portals for communication by the automotive supplier. In these themes, variations were discerned in communication channels. These differences were rooted in participants’ responsibilities, decision-making authority, and designated roles. Consequently, the perception of communication channels varied among participants. However, similarities were also noted in the participants’ feedback regarding communication channels. The research highlighted the necessity for improved two-way communication and emphasized the need for a collaborative approach between OEMs and the automotive supplier, rather than a unilateral one. The research underscored an evident power imbalance between OEMs and the automotive supplier. In essence, the crux of a successful and mutually beneficial engagement between OEMs and the automotive supplier lies in transparent communication, adaptability, and a shared willingness to find solutions that cater to both sides. By focusing on these core principles, it is plausible to establish a scenario that benefits both parties and nurtures a robust and enduring partnership. , Thesis (MBA) -- Faculty of Business and Economic Sciences, Business School, 2024
- Full Text:
- Date Issued: 2024-04
- Authors: van Staden, Shelby
- Date: 2024-04
- Subjects: Business logistics , Materials management , Automobile industry and trade -- South Africa
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/${Handle} , vital:74160
- Description: The central aim of this study was to assess the engagement of supply chain stakeholders, namely OEMs and an automotive supplier, in relation to customer-specific requirements. This objective was accomplished by identifying the communication methods employed by both parties for addressing customer-specific needs. Additionally, the study aimed to pinpoint the factors that promoted engagement between OEMs and automotive suppliers concerning these requirements. Conversely, it aimed to uncover the factors that hindered such engagement. Lastly, the research aimed to evaluate whether this engagement effectively alleviated the pressures faced by the automotive supplier regarding customer-specific requirements. The broader goal of the research was to comprehend how supply chain stakeholder engagement operated between OEMs and an automotive supplier with respect to customer-specific requirements. This was pursued through secondary objectives, which entailed examining how communication transpired between OEMs and an automotive supplier, the degree of participatory nature in this communication, the barriers and catalysts influencing customer-specific requirements, and whether this engagement mitigated the pressures borne by the automotive supplier. These objectives were instrumental in revealing opportunities for enhancing OEM communication, thereby positively contributing to their relationships with supply chain partners and mitigating the added burdens they faced. The research followed a qualitative case study design, utilizing semi-structured interviews to delve into the experiences of participants carefully selected from an automotive supplier. These participants were chosen based on their interactions with OEM customers, thereby providing pertinent insights into these interactions. Thematic analysis was employed for data analysis, uncovering codes, categories, and overarching themes from participants’ responses. The findings of the research highlighted certain consistent themes, shedding light on which communication methods were employed more frequently, as well as the rationale behind their usage. Notably, online platforms emerged as a popular channel, and daily communication was preferred. The research also revealed a recurring theme wherein OEMs assumed a controlling role, rather than fostering a mutually advantageous partnership in addressing issues. Additionally, communication barriers were observed in the use of online portals for communication by the automotive supplier. In these themes, variations were discerned in communication channels. These differences were rooted in participants’ responsibilities, decision-making authority, and designated roles. Consequently, the perception of communication channels varied among participants. However, similarities were also noted in the participants’ feedback regarding communication channels. The research highlighted the necessity for improved two-way communication and emphasized the need for a collaborative approach between OEMs and the automotive supplier, rather than a unilateral one. The research underscored an evident power imbalance between OEMs and the automotive supplier. In essence, the crux of a successful and mutually beneficial engagement between OEMs and the automotive supplier lies in transparent communication, adaptability, and a shared willingness to find solutions that cater to both sides. By focusing on these core principles, it is plausible to establish a scenario that benefits both parties and nurtures a robust and enduring partnership. , Thesis (MBA) -- Faculty of Business and Economic Sciences, Business School, 2024
- Full Text:
- Date Issued: 2024-04
Government expenditure on health services and economic development in South Africa
- Authors: Magida, Ngesisa
- Date: 2024-00
- Subjects: Government expenditure on health services
- Language: English
- Type: Masters theses , text
- Identifier: http://hdl.handle.net/11260/10146 , vital:74943
- Description: Economic development relates to economic growth and improvements in the living standards of people. South Africa is ranked among the slow developing countries in the world, based on the high percentage of people living under poor conditions. This study examines the relationship between government health expenditure and economic development in South Africa between 1994 and 2022. Human development index (HDI), government health expenditure (GHE), inflation, population growth, and unemployment are the variables used to investigate this relationship. Auto regressive distributed lag (ARDL) and Granger causality were employed to examine this relationship. Government expenditure on health services and inflation were found to have a positive short-run and long-run relationship with human development index, whereas unemployment and population growth showed a negative relationship with HDI in the long-run. Granger causality results highlighted a unidirectional causality between HDI and GHE in South Africa, among other explanatory variables. HDI Granger causes GHE and vice versa. Continuous increment and monitoring of GHE distribution, to ensure that the growing population receives proper healthcare to boost the life expectancy of the citizens and to fund the preventative measures against health epidemics in South Africa is the policy recommendation to improve HDI in South Africa. Keywords: , Thesis (Masters) -- Faculty of Economics and Financial Sciences, 2024
- Full Text:
- Date Issued: 2024-00
- Authors: Magida, Ngesisa
- Date: 2024-00
- Subjects: Government expenditure on health services
- Language: English
- Type: Masters theses , text
- Identifier: http://hdl.handle.net/11260/10146 , vital:74943
- Description: Economic development relates to economic growth and improvements in the living standards of people. South Africa is ranked among the slow developing countries in the world, based on the high percentage of people living under poor conditions. This study examines the relationship between government health expenditure and economic development in South Africa between 1994 and 2022. Human development index (HDI), government health expenditure (GHE), inflation, population growth, and unemployment are the variables used to investigate this relationship. Auto regressive distributed lag (ARDL) and Granger causality were employed to examine this relationship. Government expenditure on health services and inflation were found to have a positive short-run and long-run relationship with human development index, whereas unemployment and population growth showed a negative relationship with HDI in the long-run. Granger causality results highlighted a unidirectional causality between HDI and GHE in South Africa, among other explanatory variables. HDI Granger causes GHE and vice versa. Continuous increment and monitoring of GHE distribution, to ensure that the growing population receives proper healthcare to boost the life expectancy of the citizens and to fund the preventative measures against health epidemics in South Africa is the policy recommendation to improve HDI in South Africa. Keywords: , Thesis (Masters) -- Faculty of Economics and Financial Sciences, 2024
- Full Text:
- Date Issued: 2024-00
In-silico investigation of the effects of genetic mutations on the structural dynamics of thiopurine s-methyltransferase and their implications on the metabolism of 6-mercaptopurine
- Authors: Mwaniki, Rehema Mukami
- Date: 2023-10-13
- Subjects: Mutation , Thiopurine S-methyltransferase , Mercaptopurine , Molecular dynamics , Protein structure , Structural dynamics
- Language: English
- Type: Academic theses , Master's theses , text
- Identifier: http://hdl.handle.net/10962/432553 , vital:72880
- Description: Thiopurine S-methyltransferase (TPMT) is a cytosolic enzyme that catalyzes the S-methylation of aromatic and heterocyclic sulfhydryl compounds such as 6-mercaptopurine (6MP), 6-thioguanine (6TG) and azathioprine (AZA) which is first converted to 6MP through reduction by glutathione S- transferases (GST). The compounds, generally referred to as thiopurines, are immunosuppressants used to treat childhood acute lymphoblastic leukemia (ALL), autoimmune disorders and transplant rejection. Thiopurines are prodrugs which require metabolic activation to give thioguanine nucleotides that exert their cytotoxic effects by incorporation into DNA or inhibiting purine synthesis. The methylation reaction by TPMT utilizing S-adenosylmethionine (SAM) as the methyl donor prevents their conversion to these toxic compounds. The catalytic activity of TPMT in metabolising these compounds has been associated with occurrence of genetic variations. The variations that result to missense mutations cause amino-acid changes and in turn alter the polypeptide sequence of the protein. This could alter functionality and structural dynamics of the enzyme. This study sought to understand the underlying mechanism by which 7 specially selected mutations impede metabolic activity of the enzyme on 6-MP using in silico techniques. VAPOR and PredictSNP were used to predict the effects of single nucleotide polymorphisms (SNPs) on the stability and function of the enzyme. Of the 7 mutations, only H227Q was predicted to be functionally benign while the rest (L49S, L69V, A80P, R163H, R163C and R163P) were predicted to be deleterious or associated with disease. All the SNPs were predicted to destabilize the enzyme. Molecular dynamics (MD) simulations were preformed to mimic the behaviour of the apo, holo and drug-bound WT and mutant enzymes in vivo. This was followed by post-MD analysis to identify changes in the local and global motions of the protein in the presence of mutations and changes in intra-protein communication networks through contact map and centrality metrics calculations. RMSD and Rg analyses were performed to assess changes in global motions and compactness of the enzyme in the apo, holo and drug-bound states and in the presence of mutations. These revealed that binding of the ligand had a stabilizing effect on the WT enzyme evident from more steady trends from the analyses across trajectories in the holo and drug-bound enzymes compared to the apoenzyme. The occurrence of mutations had an effect on the global motions and compactness of the enzyme across the trajectories. Most mutations resulted in destabilized systems and less compact structures shown by unsteady RMSD and Rg across trajectories respectively. The drugbound systems appeared to be more stable in most of the systems meaning that the binding of 6MP stabilized the enzyme regardless of the presence of a mutation. RMSF analysis recorded local changes in residue flexibility due to the presence of mutations in all the systems. All the drug-bound mutant systems lost flexibility on the αAhelix which caps the active site. This could have an effect on drug binding and result to defective drug metabolism. The A80P mutation resulted to a more rigid structure from both global and local motions compared to the WT enzyme which could be associated with its nearly loss of function in vivo and in vitro. Dynamic cross correlation calculations were performed to assess how the atoms moved together. Correlated, anti-correlated and areas of no correlations were recorded in all the systems and in similar places when compared to each other. This meant that occurrence of mutations had no effect on how the atoms moved together. Contact map analysis showed that occurrence of mutations caused changes in interactions around the positions where the mutations occurred, which could have an effect on protein structural dynamics. The A80P substitution which occurred on the surface away from the binding site was identified as an allosteric mutation that resulted to changes in the catalytic site. Contact maps for the drug-cofactor complex in the mutant systems in comparison with the WT protein revealed changes that could suggest reorientation of the drug at the catalytic site. This could be an implication to altered drug metabolism. Eigenvector centrality (EC) and betweenness centrality (BC) for the most equilibrated portions of the trajectories were calculated for all the studied systems to identify residues connected to the most important residues and those that were spanned the most in shortest paths connecting other residues. Areas that scored highest in these metrics where mostly found in regions surrounding the catalytic site. Top 5% centrality hubs calculations showed loss of major hubs due to mutations with gaining of new ones. This means that mutations affected communication networks within the protein. The gained hubs were in areas close-by the lost ones which could have been an attempt of the protein to accommodate the mutations. Persistent top 5% BC hubs were identified at positions 90 and 151 while one persistent top 5% EC hub was identified at position 70. This positions play important roles in shaping the catalytic site and are in direct contact with the ligands. It was concluded that in silico techniques and analysis applied in this study revealed possible mechanisms in which genetic variations affected the structural dynamics of TMPT enzyme an affecte 6MP metabolism. , Thesis (MSc) -- Faculty of Science, Biochemistry and Microbiology, 2023
- Full Text:
- Date Issued: 2023-10-13
- Authors: Mwaniki, Rehema Mukami
- Date: 2023-10-13
- Subjects: Mutation , Thiopurine S-methyltransferase , Mercaptopurine , Molecular dynamics , Protein structure , Structural dynamics
- Language: English
- Type: Academic theses , Master's theses , text
- Identifier: http://hdl.handle.net/10962/432553 , vital:72880
- Description: Thiopurine S-methyltransferase (TPMT) is a cytosolic enzyme that catalyzes the S-methylation of aromatic and heterocyclic sulfhydryl compounds such as 6-mercaptopurine (6MP), 6-thioguanine (6TG) and azathioprine (AZA) which is first converted to 6MP through reduction by glutathione S- transferases (GST). The compounds, generally referred to as thiopurines, are immunosuppressants used to treat childhood acute lymphoblastic leukemia (ALL), autoimmune disorders and transplant rejection. Thiopurines are prodrugs which require metabolic activation to give thioguanine nucleotides that exert their cytotoxic effects by incorporation into DNA or inhibiting purine synthesis. The methylation reaction by TPMT utilizing S-adenosylmethionine (SAM) as the methyl donor prevents their conversion to these toxic compounds. The catalytic activity of TPMT in metabolising these compounds has been associated with occurrence of genetic variations. The variations that result to missense mutations cause amino-acid changes and in turn alter the polypeptide sequence of the protein. This could alter functionality and structural dynamics of the enzyme. This study sought to understand the underlying mechanism by which 7 specially selected mutations impede metabolic activity of the enzyme on 6-MP using in silico techniques. VAPOR and PredictSNP were used to predict the effects of single nucleotide polymorphisms (SNPs) on the stability and function of the enzyme. Of the 7 mutations, only H227Q was predicted to be functionally benign while the rest (L49S, L69V, A80P, R163H, R163C and R163P) were predicted to be deleterious or associated with disease. All the SNPs were predicted to destabilize the enzyme. Molecular dynamics (MD) simulations were preformed to mimic the behaviour of the apo, holo and drug-bound WT and mutant enzymes in vivo. This was followed by post-MD analysis to identify changes in the local and global motions of the protein in the presence of mutations and changes in intra-protein communication networks through contact map and centrality metrics calculations. RMSD and Rg analyses were performed to assess changes in global motions and compactness of the enzyme in the apo, holo and drug-bound states and in the presence of mutations. These revealed that binding of the ligand had a stabilizing effect on the WT enzyme evident from more steady trends from the analyses across trajectories in the holo and drug-bound enzymes compared to the apoenzyme. The occurrence of mutations had an effect on the global motions and compactness of the enzyme across the trajectories. Most mutations resulted in destabilized systems and less compact structures shown by unsteady RMSD and Rg across trajectories respectively. The drugbound systems appeared to be more stable in most of the systems meaning that the binding of 6MP stabilized the enzyme regardless of the presence of a mutation. RMSF analysis recorded local changes in residue flexibility due to the presence of mutations in all the systems. All the drug-bound mutant systems lost flexibility on the αAhelix which caps the active site. This could have an effect on drug binding and result to defective drug metabolism. The A80P mutation resulted to a more rigid structure from both global and local motions compared to the WT enzyme which could be associated with its nearly loss of function in vivo and in vitro. Dynamic cross correlation calculations were performed to assess how the atoms moved together. Correlated, anti-correlated and areas of no correlations were recorded in all the systems and in similar places when compared to each other. This meant that occurrence of mutations had no effect on how the atoms moved together. Contact map analysis showed that occurrence of mutations caused changes in interactions around the positions where the mutations occurred, which could have an effect on protein structural dynamics. The A80P substitution which occurred on the surface away from the binding site was identified as an allosteric mutation that resulted to changes in the catalytic site. Contact maps for the drug-cofactor complex in the mutant systems in comparison with the WT protein revealed changes that could suggest reorientation of the drug at the catalytic site. This could be an implication to altered drug metabolism. Eigenvector centrality (EC) and betweenness centrality (BC) for the most equilibrated portions of the trajectories were calculated for all the studied systems to identify residues connected to the most important residues and those that were spanned the most in shortest paths connecting other residues. Areas that scored highest in these metrics where mostly found in regions surrounding the catalytic site. Top 5% centrality hubs calculations showed loss of major hubs due to mutations with gaining of new ones. This means that mutations affected communication networks within the protein. The gained hubs were in areas close-by the lost ones which could have been an attempt of the protein to accommodate the mutations. Persistent top 5% BC hubs were identified at positions 90 and 151 while one persistent top 5% EC hub was identified at position 70. This positions play important roles in shaping the catalytic site and are in direct contact with the ligands. It was concluded that in silico techniques and analysis applied in this study revealed possible mechanisms in which genetic variations affected the structural dynamics of TMPT enzyme an affecte 6MP metabolism. , Thesis (MSc) -- Faculty of Science, Biochemistry and Microbiology, 2023
- Full Text:
- Date Issued: 2023-10-13
Drive for show: putt for dough?: The value of performance measures for professional golfers on the Sunshine Tour and the relationship with earnings
- Authors: Heathfield, Cameron Spencer
- Date: 2023-03-31
- Subjects: Sports Economic aspects South Africa , Golfers South Africa , PGA Sunshine Tour (Association) , Production functions (Economic theory) , Marginal productivity , Performance measurement
- Language: English
- Type: Academic theses , Master's theses , text
- Identifier: http://hdl.handle.net/10962/419499 , vital:71649
- Description: “Drive for show, putt for dough”. This controversial adage has been a prominent sentiment in the game of golf for decades. Empirical evidence investigating its robustness through determinant of earnings inquiries have identified that the most valuable measure of performance in golf is in fact putting. However, with the ever-perpetuating state of golf equipment and the technologies thereof, the distance debate in golf has thus gained traction. Recent investigations and evidence into the adage had identified a trend-shift with regards to the value associated with distance achievable and putting ability in golf. Therefore questioning the relevance of the adage in the modern form of the game. In conducting a determinant of earnings inquiry through the engagement of engineering “pure” performance measures as empirically identified, this investigation is aimed at recognising a similar trend in a South African perspective, on the Sunshine Tour. Utilising a generalised least square regression methodology, the analysis identifies how the value of the marginal product as-sociated with both player and non-player explanatory measures influence real earnings on the Sun-shine Tour. This determination is observed through the means of a comprehensive scenario analysis, demonstrating the effect of marginal performance differences to the degree of 1% and 5% increase in performance. A trend was therefore identified in which the value of the marginal product, and growth in real earnings associated to driving distance at the 5% level were in fact greater than the that of putting ability. The results further denote the robustness of the adage and the inherent value associated to putting vs. driving distance at the 1% level. The conclusion to this investigation demonstrates the importance of opportunistic positions player’s put themselves in within tournaments to encourage earnings accumulation. Identified through balanced return on investments for all performance measures to “drive for dough to putt for dough”. , Thesis (MEcon) -- Faculty of Commerce, Economics and Economics History, 2023
- Full Text:
- Date Issued: 2023-03-31
- Authors: Heathfield, Cameron Spencer
- Date: 2023-03-31
- Subjects: Sports Economic aspects South Africa , Golfers South Africa , PGA Sunshine Tour (Association) , Production functions (Economic theory) , Marginal productivity , Performance measurement
- Language: English
- Type: Academic theses , Master's theses , text
- Identifier: http://hdl.handle.net/10962/419499 , vital:71649
- Description: “Drive for show, putt for dough”. This controversial adage has been a prominent sentiment in the game of golf for decades. Empirical evidence investigating its robustness through determinant of earnings inquiries have identified that the most valuable measure of performance in golf is in fact putting. However, with the ever-perpetuating state of golf equipment and the technologies thereof, the distance debate in golf has thus gained traction. Recent investigations and evidence into the adage had identified a trend-shift with regards to the value associated with distance achievable and putting ability in golf. Therefore questioning the relevance of the adage in the modern form of the game. In conducting a determinant of earnings inquiry through the engagement of engineering “pure” performance measures as empirically identified, this investigation is aimed at recognising a similar trend in a South African perspective, on the Sunshine Tour. Utilising a generalised least square regression methodology, the analysis identifies how the value of the marginal product as-sociated with both player and non-player explanatory measures influence real earnings on the Sun-shine Tour. This determination is observed through the means of a comprehensive scenario analysis, demonstrating the effect of marginal performance differences to the degree of 1% and 5% increase in performance. A trend was therefore identified in which the value of the marginal product, and growth in real earnings associated to driving distance at the 5% level were in fact greater than the that of putting ability. The results further denote the robustness of the adage and the inherent value associated to putting vs. driving distance at the 1% level. The conclusion to this investigation demonstrates the importance of opportunistic positions player’s put themselves in within tournaments to encourage earnings accumulation. Identified through balanced return on investments for all performance measures to “drive for dough to putt for dough”. , Thesis (MEcon) -- Faculty of Commerce, Economics and Economics History, 2023
- Full Text:
- Date Issued: 2023-03-31
“It’s not just me on a video call with someone…” Students’ experiences of a forced transition from face-to-face psychotherapy to online psychotherapy during COVID-19: an interpretative phenomenological analysis
- Authors: Keet, Nicole Tahnee
- Date: 2023-03-30
- Subjects: Online therapy , COVID-19 Pandemic, 2020- Influence , Interpretative phenomenological analysis , Psychologists Training of , College students Attitudes
- Language: English
- Type: Academic theses , Master's theses , text
- Identifier: http://hdl.handle.net/10962/408845 , vital:70531
- Description: The aim of this study is to explore university students’ experience of a forced transition from face-to-face therapy to online therapy during COVID-19. This pandemic was unexpected and affected all areas of life, including the closure of universities, which left therapists and clients alike unsure of how to navigate these unchartered territories. Although there is a considerable amount of international research on experiences of online therapy, there is little research on a forced transition to online therapy because of COVID-19 and even less within the South African context. A sample of six participants between the ages of 20 and 30 years old were selected through purposive and convenience sampling. Semi-structured interviews were conducted, and interpretative Phenomenological Analysis (IPA) was utilised to ascertain how participants make sense of their worlds in relation to the transition to online therapy. The analysis provided three main superordinate themes, which are supported by subordinate themes. The superordinate themes are: 1) Online therapy as authentic and continuous, where the participants experienced the comfort and convenience of online therapy, the continuity of care and the anonymity of online therapy. 2) Online therapy as disruptive and invasive, where participants experienced issues with privacy, an intrusive environment, technological challenges, lack of body language and therapy feeling more disposable. 3) Getting used to online therapy with some help from the therapist, where participants felt an adjustment period was necessary as well as transparency and containment from the therapist to help with the transition. These findings support some existing South African literature; however, it also engages with findings unique to this study, that will hopefully be used for further exploration. The study ends with recommendations for training therapists on using online therapy. , Thesis (MA) -- Faculty of Humanities, Psychology, 2023
- Full Text:
- Date Issued: 2023-03-30
- Authors: Keet, Nicole Tahnee
- Date: 2023-03-30
- Subjects: Online therapy , COVID-19 Pandemic, 2020- Influence , Interpretative phenomenological analysis , Psychologists Training of , College students Attitudes
- Language: English
- Type: Academic theses , Master's theses , text
- Identifier: http://hdl.handle.net/10962/408845 , vital:70531
- Description: The aim of this study is to explore university students’ experience of a forced transition from face-to-face therapy to online therapy during COVID-19. This pandemic was unexpected and affected all areas of life, including the closure of universities, which left therapists and clients alike unsure of how to navigate these unchartered territories. Although there is a considerable amount of international research on experiences of online therapy, there is little research on a forced transition to online therapy because of COVID-19 and even less within the South African context. A sample of six participants between the ages of 20 and 30 years old were selected through purposive and convenience sampling. Semi-structured interviews were conducted, and interpretative Phenomenological Analysis (IPA) was utilised to ascertain how participants make sense of their worlds in relation to the transition to online therapy. The analysis provided three main superordinate themes, which are supported by subordinate themes. The superordinate themes are: 1) Online therapy as authentic and continuous, where the participants experienced the comfort and convenience of online therapy, the continuity of care and the anonymity of online therapy. 2) Online therapy as disruptive and invasive, where participants experienced issues with privacy, an intrusive environment, technological challenges, lack of body language and therapy feeling more disposable. 3) Getting used to online therapy with some help from the therapist, where participants felt an adjustment period was necessary as well as transparency and containment from the therapist to help with the transition. These findings support some existing South African literature; however, it also engages with findings unique to this study, that will hopefully be used for further exploration. The study ends with recommendations for training therapists on using online therapy. , Thesis (MA) -- Faculty of Humanities, Psychology, 2023
- Full Text:
- Date Issued: 2023-03-30
Quantifying feed intake and feeding intensity using two experimental conditions and the effect of different feeding strategies on the production parameters of farmed South African abalone, haliotis midae
- Authors: Wortley, Ross Michael
- Date: 2023-03-29
- Subjects: Uncatalogued
- Language: English
- Type: Academic theses , Master's theses , text
- Identifier: http://hdl.handle.net/${Handle} , vital:71932
- Description: As abalone are slow-growing animals there is a high investment of capital, running costs and labour in commercial abalone farming. Revenue needs to be maximised by achieving fast growth rates. A foremost driver of abalone growth is feed intake and feeding intensity of the abalone as well as the feeding regimen a farm utilises. While feed intake is well-documented in H. midae, there is a paucity of information regarding this aspect in abalone above 70 g and the relationship between feeding intensity, feed conversion rate (FCR) and daily growth rate needs to be documented. Similarly, there are a limited number of studies dealing with the effects of different pellet types of the same formulation, that differ only in shape and size, on feed intake and production in H. midae. This study made use of both a controlled laboratory experiment and commercial-scale farm experiment with the aim of testing whether feed intake information produced under laboratory conditions can provide good estimates of feed intake under farming conditions, which can further be implemented into feeding strategies on abalone farms. This study quantified daily feed intake (F) in 10 – 20 g, 100 – 110 g and 150 – 160 g abalone weight classes using two different pellet types and determined the relationship between the duration of feed availability and feed intake under laboratory conditions. The effect of three different pellet type strategies (fed daily: a leaf-only strategy = L d-1, a short-pellet only strategy = SP d-1, and a strategy that used both = B d-1) on abalone production parameters under farming conditions such as growth rate, feed conversion ratio (FCR), feeding intensity (FI) and weight variation of 30 – 40 g H. midae was also investigated. A commercial-scale farm study was designed to test the effect of four commercially relevant feeding regimens (three size-specific regimens and one commercially practiced feeding method) on the growth, FCR, feeding intensity and weight variation of these three abalone weight classes while taking into account an economic model to assess the profitability of each feeding regimen. Daily feed intake as a percentage of body mass (% BM d-1) was a function of abalone weight class between the 10 – 20 g and two larger weight classes 100 – 110 g and 150 – 160 g p < 0.0001), however feed intake was not different between the 100 – 110 g and 150 – 160 g weight classes. Pellet type did not affect feed intake in all abalone weight classes (p = 0.15). Feed intake (F) was positively linearly correlated with duration of feed availability (h) in the 10 – 20 g weight class (r2 = 0.76, p <0.00001) and logarithmically correlated in the 100 – 110 g (r2 = 0.25, p < 0.02) and 150 – 160 g (r2 = 0.52, p < 0.0001) weight classes (10 – 20 g abalone-1: 3 F (% BM) = 0.02(h) + 0.1976, 100 – 110 g abalone-1: F (% BM) = log10(h)*0.17 + 0.17, 150 – 160 g abalone-1: F (% BM) = log10(h)*0.36 + 0.07). There was no significant difference in monthly average abalone weight, daily growth rate (G), FCR and feeding intensity between each pellet type strategy (G: p = 0.60, FCR: p = 0.62, FI: p = 0.54 ). However, abalone grew well over the 112-day growth period with average abalone weight increasing significantly between each monthly sample time (pooled pellet type strategy: Huynh-Feldt correction; p < 0.00001). Furthermore, abalone fed the leaf-only pellet type strategy (L d-1) fell into higher weight classes after a 112-day growth period (Z test: 50 – 70 g: 72%) which was 16.1 % higher compared to the SP d-1 and B d-1 strategies. Daily growth rate (r2 = 0.34, p < 0.01) and FCR (r2 = 0.42, p < 0.004) was negatively correlated and FCR was positively correlated with daily feeding intensity, respectively (G = - 2.59 (FI) + 1.526, FCR = 8.8082 (FI) – 2.7108). Feeding regimen affected the production parameters of three abalone weight classes. The method practiced on the farm resulted in the best growth in the 10 – 20 g abalone weight class. The farm feeding method resulted in slower yet more efficient growth rates (lowest FCR values) in the abalone weight classes, 100 – 110 g and 150 – 160 g abalone- 1. However, size-specific feeding regimens resulted in the fastest growth rates but resulted in higher FCR values (less efficient). The relationship between feeding intensity, daily growth rate and FCR all showed that an increase in feeding intensity results in increased daily growth rates and FCR values. The economic model suggests that the higher FCR values associated with size-specific regimens, which have higher associated costs to producing abalone, were greatly outweighed by the growth attained by the abalone in the 100 – 110 g and 150 – 160 g weight classes. The size-specific regimens generated a higher potential monetary value of abalone after a 112-day period, which would consequently result in higher income for abalone farms. For abalone ranging from 100 – 110 and 150 – 160 grams, the economic model suggested that in a quarterly grading schedule (112 days) that abalone be fed the size specific daily rations, which is a function of body mass, at 0.35 % BM d-1 and 0.352 % BM d-1, respectively. The two experimental conditions used in this study produced feed intake and production parameter information that is beneficial to South African abalone farmers. The small-scale laboratory study produced information on feed intake that can be used as reference values as to what abalone in these weight classes can consume on a daily basis. The laboratory study can provide estimates of feed intake under farming conditions but should only be used as minimum 4 values when determining size-specific feeding regimens. To maximise abalone growth, farmers should utilise size-specific feeding regimens for abalone above 30 g. Daily growth rate and FCR can be predicted as a function of the abalone’s feeding intensity. Further studies are needed to determine the effects of abalone weight class on production parameters when testing different pellet types as well as an exploration into behavioural studies focusing on diet preferences. Additionally, future studies need to take into consideration abalone above the weight of 100 g with additional focus of research on behavioural, genetic and environmental aspects on abalone feed intake. , Thesis (MSc) -- Faculty of Science, Ichthyology and Fisheries Science, 2023
- Full Text:
- Date Issued: 2023-03-29
- Authors: Wortley, Ross Michael
- Date: 2023-03-29
- Subjects: Uncatalogued
- Language: English
- Type: Academic theses , Master's theses , text
- Identifier: http://hdl.handle.net/${Handle} , vital:71932
- Description: As abalone are slow-growing animals there is a high investment of capital, running costs and labour in commercial abalone farming. Revenue needs to be maximised by achieving fast growth rates. A foremost driver of abalone growth is feed intake and feeding intensity of the abalone as well as the feeding regimen a farm utilises. While feed intake is well-documented in H. midae, there is a paucity of information regarding this aspect in abalone above 70 g and the relationship between feeding intensity, feed conversion rate (FCR) and daily growth rate needs to be documented. Similarly, there are a limited number of studies dealing with the effects of different pellet types of the same formulation, that differ only in shape and size, on feed intake and production in H. midae. This study made use of both a controlled laboratory experiment and commercial-scale farm experiment with the aim of testing whether feed intake information produced under laboratory conditions can provide good estimates of feed intake under farming conditions, which can further be implemented into feeding strategies on abalone farms. This study quantified daily feed intake (F) in 10 – 20 g, 100 – 110 g and 150 – 160 g abalone weight classes using two different pellet types and determined the relationship between the duration of feed availability and feed intake under laboratory conditions. The effect of three different pellet type strategies (fed daily: a leaf-only strategy = L d-1, a short-pellet only strategy = SP d-1, and a strategy that used both = B d-1) on abalone production parameters under farming conditions such as growth rate, feed conversion ratio (FCR), feeding intensity (FI) and weight variation of 30 – 40 g H. midae was also investigated. A commercial-scale farm study was designed to test the effect of four commercially relevant feeding regimens (three size-specific regimens and one commercially practiced feeding method) on the growth, FCR, feeding intensity and weight variation of these three abalone weight classes while taking into account an economic model to assess the profitability of each feeding regimen. Daily feed intake as a percentage of body mass (% BM d-1) was a function of abalone weight class between the 10 – 20 g and two larger weight classes 100 – 110 g and 150 – 160 g p < 0.0001), however feed intake was not different between the 100 – 110 g and 150 – 160 g weight classes. Pellet type did not affect feed intake in all abalone weight classes (p = 0.15). Feed intake (F) was positively linearly correlated with duration of feed availability (h) in the 10 – 20 g weight class (r2 = 0.76, p <0.00001) and logarithmically correlated in the 100 – 110 g (r2 = 0.25, p < 0.02) and 150 – 160 g (r2 = 0.52, p < 0.0001) weight classes (10 – 20 g abalone-1: 3 F (% BM) = 0.02(h) + 0.1976, 100 – 110 g abalone-1: F (% BM) = log10(h)*0.17 + 0.17, 150 – 160 g abalone-1: F (% BM) = log10(h)*0.36 + 0.07). There was no significant difference in monthly average abalone weight, daily growth rate (G), FCR and feeding intensity between each pellet type strategy (G: p = 0.60, FCR: p = 0.62, FI: p = 0.54 ). However, abalone grew well over the 112-day growth period with average abalone weight increasing significantly between each monthly sample time (pooled pellet type strategy: Huynh-Feldt correction; p < 0.00001). Furthermore, abalone fed the leaf-only pellet type strategy (L d-1) fell into higher weight classes after a 112-day growth period (Z test: 50 – 70 g: 72%) which was 16.1 % higher compared to the SP d-1 and B d-1 strategies. Daily growth rate (r2 = 0.34, p < 0.01) and FCR (r2 = 0.42, p < 0.004) was negatively correlated and FCR was positively correlated with daily feeding intensity, respectively (G = - 2.59 (FI) + 1.526, FCR = 8.8082 (FI) – 2.7108). Feeding regimen affected the production parameters of three abalone weight classes. The method practiced on the farm resulted in the best growth in the 10 – 20 g abalone weight class. The farm feeding method resulted in slower yet more efficient growth rates (lowest FCR values) in the abalone weight classes, 100 – 110 g and 150 – 160 g abalone- 1. However, size-specific feeding regimens resulted in the fastest growth rates but resulted in higher FCR values (less efficient). The relationship between feeding intensity, daily growth rate and FCR all showed that an increase in feeding intensity results in increased daily growth rates and FCR values. The economic model suggests that the higher FCR values associated with size-specific regimens, which have higher associated costs to producing abalone, were greatly outweighed by the growth attained by the abalone in the 100 – 110 g and 150 – 160 g weight classes. The size-specific regimens generated a higher potential monetary value of abalone after a 112-day period, which would consequently result in higher income for abalone farms. For abalone ranging from 100 – 110 and 150 – 160 grams, the economic model suggested that in a quarterly grading schedule (112 days) that abalone be fed the size specific daily rations, which is a function of body mass, at 0.35 % BM d-1 and 0.352 % BM d-1, respectively. The two experimental conditions used in this study produced feed intake and production parameter information that is beneficial to South African abalone farmers. The small-scale laboratory study produced information on feed intake that can be used as reference values as to what abalone in these weight classes can consume on a daily basis. The laboratory study can provide estimates of feed intake under farming conditions but should only be used as minimum 4 values when determining size-specific feeding regimens. To maximise abalone growth, farmers should utilise size-specific feeding regimens for abalone above 30 g. Daily growth rate and FCR can be predicted as a function of the abalone’s feeding intensity. Further studies are needed to determine the effects of abalone weight class on production parameters when testing different pellet types as well as an exploration into behavioural studies focusing on diet preferences. Additionally, future studies need to take into consideration abalone above the weight of 100 g with additional focus of research on behavioural, genetic and environmental aspects on abalone feed intake. , Thesis (MSc) -- Faculty of Science, Ichthyology and Fisheries Science, 2023
- Full Text:
- Date Issued: 2023-03-29
Attitudes and barriers towards HIV testing services among males aged between 15-49 years at Mzamomhle Township: Buffalo City Metropolitan Municipality
- Authors: Mantashe, Zintle
- Date: 2023-00
- Subjects: Public Health
- Language: English
- Type: Masters theses , text
- Identifier: http://hdl.handle.net/11260/9753 , vital:74617
- Description: This study delves into the attitudes and obstacles surrounding HIV Testing Services (HTS) among males aged 15 to 49 in Mzamomhle Township, Buffalo City Metropolitan Municipality, South Africa. HIV/AIDS prevalence remains a significant concern, especially in sub-Saharan Africa. Employing a mixed-methods approach with questionnaires and interviews, data was gathered from 106 participants. The findings highlight a range of challenges that impede the accessibility of HTS. These challenges include stigma, concerns about privacy, fears related to testing, limited knowledge, and negative attitudes of staff towards HTS. Despite these challenges, the study reveals that participants generally hold positive attitudes towards HTS. However, there are doubts regarding the efficacy of testing in preventing the transmission of HIV. Privacy concerns emerge prominently, with participants fearing that their status might be disclosed. Stigma also acts as a barrier, as individuals fear potential embarrassment if their status becomes known. To address these issues, several recommendations are proposed. These include the establishment of robust support systems, educational campaigns to empower individuals with knowledge about HTS benefits, and community initiatives to combat negative attitudes towards testing. Furthermore, enhancing healthcare worker training and raising political awareness can contribute to creating a more favourable environment for HTS utilisation. By implementing these recommendations, South Africa can work towards dismantling the barriers that hinder HIV testing and promoting a proactive culture of health-seeking behaviour among men. This effort is essential for reducing HIV transmission rates and achieving global health targets. , Thesis (Masters) -- Faculty of Medicine and Health Sciences, 2023
- Full Text:
- Date Issued: 2023-00
- Authors: Mantashe, Zintle
- Date: 2023-00
- Subjects: Public Health
- Language: English
- Type: Masters theses , text
- Identifier: http://hdl.handle.net/11260/9753 , vital:74617
- Description: This study delves into the attitudes and obstacles surrounding HIV Testing Services (HTS) among males aged 15 to 49 in Mzamomhle Township, Buffalo City Metropolitan Municipality, South Africa. HIV/AIDS prevalence remains a significant concern, especially in sub-Saharan Africa. Employing a mixed-methods approach with questionnaires and interviews, data was gathered from 106 participants. The findings highlight a range of challenges that impede the accessibility of HTS. These challenges include stigma, concerns about privacy, fears related to testing, limited knowledge, and negative attitudes of staff towards HTS. Despite these challenges, the study reveals that participants generally hold positive attitudes towards HTS. However, there are doubts regarding the efficacy of testing in preventing the transmission of HIV. Privacy concerns emerge prominently, with participants fearing that their status might be disclosed. Stigma also acts as a barrier, as individuals fear potential embarrassment if their status becomes known. To address these issues, several recommendations are proposed. These include the establishment of robust support systems, educational campaigns to empower individuals with knowledge about HTS benefits, and community initiatives to combat negative attitudes towards testing. Furthermore, enhancing healthcare worker training and raising political awareness can contribute to creating a more favourable environment for HTS utilisation. By implementing these recommendations, South Africa can work towards dismantling the barriers that hinder HIV testing and promoting a proactive culture of health-seeking behaviour among men. This effort is essential for reducing HIV transmission rates and achieving global health targets. , Thesis (Masters) -- Faculty of Medicine and Health Sciences, 2023
- Full Text:
- Date Issued: 2023-00
Prevalence and Risk Factors of Traumatic Lumbar Puncture in Children at Nelson Mandela Central Hospital, Mthatha, Eastern Cape Province, South Africa
- Authors: Ghu, Pumza
- Date: 2023-00
- Subjects: Medicine
- Language: English
- Type: Masters theses , text
- Identifier: http://hdl.handle.net/11260/9879 , vital:74636
- Description: Traumatic lumbar puncture signals improper procedural and proceduralist factors working on existing patient attributes. Occurrence is very common though believed to be overestimated and cut-off definitions are vague. Complications that follow incurs economic implications to the hospital setting due to high admission rate, long hospital stay and unnecessary use of antibiotics. None of these concepts around this topic is known in the present setting thus necessitating this research. The findings thereof would cause a fundamental change in the manner in which this procedure is performed in the present setting. Aim To determine the prevalence and risk factors of traumatic lumbar punctures, with the secondary goal of developing a protocol for performing appropriate lumbar punctures in order to reduce the rate of traumatic lumbar punctures. Methods An analytical cross-sectional data using retrospective data of 82 lumbar punctures performed over a four (4) month period from March to June 2022 at the paediatric emergency department of Nelson Mandela Central Hospital. Results Demographics characteristics: The median age was two (2) years (IQR = 0.83 – 3.35 years) and the highest proportion (53.66%) was observed for the age group two years and younger. Males constituted more than half (63.41%) of the population. Clinical features: Most of the children presented with seizures (56.10%) and high fever (46.34%). The top three conditions diagnosed were febrile seizures (40.24%), meningitis (17.07%) and acute gastroenteritis (9.78%). More females (20% p=0.047) suffered from acute gastroenteritis than males (3.8%). , Thesis (Masters) -- Faculty of Medicine and Health Sciences, 2023
- Full Text:
- Date Issued: 2023-00
- Authors: Ghu, Pumza
- Date: 2023-00
- Subjects: Medicine
- Language: English
- Type: Masters theses , text
- Identifier: http://hdl.handle.net/11260/9879 , vital:74636
- Description: Traumatic lumbar puncture signals improper procedural and proceduralist factors working on existing patient attributes. Occurrence is very common though believed to be overestimated and cut-off definitions are vague. Complications that follow incurs economic implications to the hospital setting due to high admission rate, long hospital stay and unnecessary use of antibiotics. None of these concepts around this topic is known in the present setting thus necessitating this research. The findings thereof would cause a fundamental change in the manner in which this procedure is performed in the present setting. Aim To determine the prevalence and risk factors of traumatic lumbar punctures, with the secondary goal of developing a protocol for performing appropriate lumbar punctures in order to reduce the rate of traumatic lumbar punctures. Methods An analytical cross-sectional data using retrospective data of 82 lumbar punctures performed over a four (4) month period from March to June 2022 at the paediatric emergency department of Nelson Mandela Central Hospital. Results Demographics characteristics: The median age was two (2) years (IQR = 0.83 – 3.35 years) and the highest proportion (53.66%) was observed for the age group two years and younger. Males constituted more than half (63.41%) of the population. Clinical features: Most of the children presented with seizures (56.10%) and high fever (46.34%). The top three conditions diagnosed were febrile seizures (40.24%), meningitis (17.07%) and acute gastroenteritis (9.78%). More females (20% p=0.047) suffered from acute gastroenteritis than males (3.8%). , Thesis (Masters) -- Faculty of Medicine and Health Sciences, 2023
- Full Text:
- Date Issued: 2023-00
Investigation of thermal and electrical characteristics of crystalline silicon photovoltaic modules under varying operational conditions
- Authors: Vumbugwa, Monphias
- Date: 2022-12
- Subjects: Photovoltaic power generation -- South Africa , Silicon crystals -- South Africa , Solar cells
- Language: English
- Type: Doctoral theses , text
- Identifier: http://hdl.handle.net/10948/60014 , vital:62733
- Description: Solar energy has become an attractive and environmentally mindful method in electrical power generation as it contributes significantly to meeting the high demand for the power needed for socio and economic developments. The rise in deployment of Photovoltaic (PV) facilities with large capacity creates the need for accurate and reliable PV inspection techniques for optimum performance, the longevity of PV modules and quick return on PV investment. The performance of PV modules in the field is often monitored through several inspection methods that require a rapid throughput such as Thermal Infrared (TIR) imaging and current-voltage (I-V) measurements. Unmanned Aerial Vehicle (UAV) based TIR imaging is widely applied in large PV plants since it is cost-effective and is usually conducted in-situ while the plant is operating at irradiance levels above 600 W.m-2 . One of the outcomes of the interpretations of TIR images is an attempt to quantify the energy loss in PV plants associated with the abnormal thermal signatures identified on TIR images. No standard procedure has yet outlined the quantification of energy loss related to TIR images of underperforming modules since the interpretation of TIR images remains a challenge. PV modules operate under dynamic operating conditions which can influence the results and interpretation of thermal and electrical characterisation measurements. Dynamic operation conditions refer to any disorders in the operation of the modules and cells which cause a change in the current and voltage characteristics of the PV source. These dynamic operation conditions include; changesin load conditions, irradiance, soiling and shading levels. The tests were done under steady state conditions. Although measurements are generally done while the operating conditions are as steady as possible, some changes in conditions have a profound effect on thermal and electrical measurements. In this study, these effects and some of the changes in conditions that cause them were studied. , Thesis (PhD) -- Faculty of Science, School of Computer Science, Mathematics, Physics and Statistics, 2022
- Full Text:
- Date Issued: 2022-12
- Authors: Vumbugwa, Monphias
- Date: 2022-12
- Subjects: Photovoltaic power generation -- South Africa , Silicon crystals -- South Africa , Solar cells
- Language: English
- Type: Doctoral theses , text
- Identifier: http://hdl.handle.net/10948/60014 , vital:62733
- Description: Solar energy has become an attractive and environmentally mindful method in electrical power generation as it contributes significantly to meeting the high demand for the power needed for socio and economic developments. The rise in deployment of Photovoltaic (PV) facilities with large capacity creates the need for accurate and reliable PV inspection techniques for optimum performance, the longevity of PV modules and quick return on PV investment. The performance of PV modules in the field is often monitored through several inspection methods that require a rapid throughput such as Thermal Infrared (TIR) imaging and current-voltage (I-V) measurements. Unmanned Aerial Vehicle (UAV) based TIR imaging is widely applied in large PV plants since it is cost-effective and is usually conducted in-situ while the plant is operating at irradiance levels above 600 W.m-2 . One of the outcomes of the interpretations of TIR images is an attempt to quantify the energy loss in PV plants associated with the abnormal thermal signatures identified on TIR images. No standard procedure has yet outlined the quantification of energy loss related to TIR images of underperforming modules since the interpretation of TIR images remains a challenge. PV modules operate under dynamic operating conditions which can influence the results and interpretation of thermal and electrical characterisation measurements. Dynamic operation conditions refer to any disorders in the operation of the modules and cells which cause a change in the current and voltage characteristics of the PV source. These dynamic operation conditions include; changesin load conditions, irradiance, soiling and shading levels. The tests were done under steady state conditions. Although measurements are generally done while the operating conditions are as steady as possible, some changes in conditions have a profound effect on thermal and electrical measurements. In this study, these effects and some of the changes in conditions that cause them were studied. , Thesis (PhD) -- Faculty of Science, School of Computer Science, Mathematics, Physics and Statistics, 2022
- Full Text:
- Date Issued: 2022-12
Representation of history in Tsitsi Dangarembga’s trilogy – nervous conditions, the book of not and this mournable body
- Authors: Mutsambi, Tinoten
- Date: 2022-12
- Subjects: Women and literature --Zimbabwe--History --20th century , Identification (Psychology) in literature
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10948/59446 , vital:62116
- Description: This dissertation analyses Tsitsi Dangarembga’s novels Nervous Conditions (1988), The Book of Not (2006) and This Mournable Body (2018). The three novels under study capture a great deal of Zimbabwe’s history, spanning from the colonial era as depicted in Nervous Conditions, through the period before and after independence in The Book of Not, to the contemporary post independence Zimbabwe in This Mournable Body. Reading these three novels and analysing their depiction of historic events is important as they cover significant and contested epochs in Zimbabwean history, making it possible for us to examine the intersection between history and literature. Moreover, since most Zimbabwean narratives that depict the country’s history have been male authored, Dangarembga’s novels offer an interesting opportunity to study the depiction of history from a female perspective , Thesis (MA) -- Faculty of Humanities, School of Language, Media and Communication, 2022
- Full Text:
- Date Issued: 2022-12
- Authors: Mutsambi, Tinoten
- Date: 2022-12
- Subjects: Women and literature --Zimbabwe--History --20th century , Identification (Psychology) in literature
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10948/59446 , vital:62116
- Description: This dissertation analyses Tsitsi Dangarembga’s novels Nervous Conditions (1988), The Book of Not (2006) and This Mournable Body (2018). The three novels under study capture a great deal of Zimbabwe’s history, spanning from the colonial era as depicted in Nervous Conditions, through the period before and after independence in The Book of Not, to the contemporary post independence Zimbabwe in This Mournable Body. Reading these three novels and analysing their depiction of historic events is important as they cover significant and contested epochs in Zimbabwean history, making it possible for us to examine the intersection between history and literature. Moreover, since most Zimbabwean narratives that depict the country’s history have been male authored, Dangarembga’s novels offer an interesting opportunity to study the depiction of history from a female perspective , Thesis (MA) -- Faculty of Humanities, School of Language, Media and Communication, 2022
- Full Text:
- Date Issued: 2022-12
Bioethical analysis of COVID19, WASH/waste and related disaster management implications
- Authors: Iheanetu, Chidinma Uchenna
- Date: 2022-04-06
- Subjects: Uncatalogued
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10962/232250 , vital:49975
- Description: Thesis (MSc) -- Faculty of Science, Biotechnology Innovation Centre, 2022
- Full Text:
- Date Issued: 2022-04-06
- Authors: Iheanetu, Chidinma Uchenna
- Date: 2022-04-06
- Subjects: Uncatalogued
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10962/232250 , vital:49975
- Description: Thesis (MSc) -- Faculty of Science, Biotechnology Innovation Centre, 2022
- Full Text:
- Date Issued: 2022-04-06
The Impact of Direct Marketing on Consumer Buying Decisions in Mthatha’s Cosmetic Industry
- Authors: Mlobothi, Lusanda
- Date: 2022-00
- Subjects: Direct Marketing
- Language: English
- Type: Masters theses , text
- Identifier: http://hdl.handle.net/11260/8010 , vital:59302
- Description: This study aimed to investigate the impact of direct marketing on consumer buying decisions in Mthatha’s cosmetic industry. Direct marketing was measured by four dimensions, namely telemarketing, magazine advertisement, door-to-door selling and television home shopping. To achieve the aim, the research study adopted a positivist paradigm which was motivated by the quantitative approach using the explanatory research design. A self-administered questionnaire was issued to 300 respondents using the snowball sampling technique. The respondents were consumers that purchase cosmetic products sold through direct marketing channels in Mthatha. The key findings of the study, under the simple linear regression, revealed that telemarketing, magazine advertisements, and television home shopping influence consumer buying decisions in Mthatha’s cosmetic industry respectively. However, door-to-door selling does not influence consumer buying decisions in Mthatha’s cosmetic industry. Under the hierarchal regression analysis, the findings revealed that direct marketing influences consumer buying decisions after controlling for the respondents’ demographic variables (educational level, age, gender, marital status, and income level) in Mthatha’s cosmetic industry respectively. Based on the findings, policymakers should assist cosmetic organisations to progress from the manufacturing stage to the commercialisation stage. They should also provide capital and resources to small businesses to up-scale the size of the organisation. Based on the findings, this study will assist direct marketers to gain more understanding of how consumers think and the stages they undergo before making a purchase of a cosmetic product. Key words: Telemarketing, door-to-door selling, consumer buying decisions, television home shopping, magazine advertisements and direct marketing. , Thesis (Masters) -- Faculty of Commerce and Administration, 2022
- Full Text:
- Date Issued: 2022-00
- Authors: Mlobothi, Lusanda
- Date: 2022-00
- Subjects: Direct Marketing
- Language: English
- Type: Masters theses , text
- Identifier: http://hdl.handle.net/11260/8010 , vital:59302
- Description: This study aimed to investigate the impact of direct marketing on consumer buying decisions in Mthatha’s cosmetic industry. Direct marketing was measured by four dimensions, namely telemarketing, magazine advertisement, door-to-door selling and television home shopping. To achieve the aim, the research study adopted a positivist paradigm which was motivated by the quantitative approach using the explanatory research design. A self-administered questionnaire was issued to 300 respondents using the snowball sampling technique. The respondents were consumers that purchase cosmetic products sold through direct marketing channels in Mthatha. The key findings of the study, under the simple linear regression, revealed that telemarketing, magazine advertisements, and television home shopping influence consumer buying decisions in Mthatha’s cosmetic industry respectively. However, door-to-door selling does not influence consumer buying decisions in Mthatha’s cosmetic industry. Under the hierarchal regression analysis, the findings revealed that direct marketing influences consumer buying decisions after controlling for the respondents’ demographic variables (educational level, age, gender, marital status, and income level) in Mthatha’s cosmetic industry respectively. Based on the findings, policymakers should assist cosmetic organisations to progress from the manufacturing stage to the commercialisation stage. They should also provide capital and resources to small businesses to up-scale the size of the organisation. Based on the findings, this study will assist direct marketers to gain more understanding of how consumers think and the stages they undergo before making a purchase of a cosmetic product. Key words: Telemarketing, door-to-door selling, consumer buying decisions, television home shopping, magazine advertisements and direct marketing. , Thesis (Masters) -- Faculty of Commerce and Administration, 2022
- Full Text:
- Date Issued: 2022-00
An evolutionary study of legless skinks’ (Acontias Cuvier, 1817) head and vertebrae morphology
- Authors: Evlambiou, Anthony Andreas
- Date: 2021-10
- Subjects: Skinks South Africa , Acontias South Africa , Typhlosaurus South Africa , Acontias Morphology , Acontias Phylogeny , Acontias Evolution , Vertebrae , Skull Growth , Evolutionary developmental biology
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10962/190690 , vital:45018
- Description: Environmental factors and/or processes can produce differences in general shape between individuals or particular parts of individuals. Examples of these biological processes may include ontogenetic development, adaptation to local geographic factors, or long-term evolutionary diversification. An organism is not likely to be able to optimise a single structure for multiple purposes and so trade-offs are likely to occur. An example of such a structure is the cranium, as it can be used for multiple activities such as defensive and sexual behaviour, locomotion, prey capture, and ingestion. Morphological characteristics have historically been used in the description of species. Genetic analyses have gained popularity as species delineation techniques and have been particularly useful in identifying cryptic species, especially among morphological conserved species like legless skinks of the subfamily Acontinae (e.g. Acontias Cuvier, 1817 and Typhlosaurus Weigmann, 1834). However, completely doing away with morphological techniques during species descriptions is not the best option. Therefore, novel methods to identify species, especially those with similar body plans, are needed. In this dissertation, we explore the links between head shape and vertebral number to environmental pressures to determine whether the evolutionary process is driven by environmental pressures (soil or biome) or is retained through ancestry. A novel species/clade delineation linked to vertebral number is also investigated. Head shape was expected to have a close link to the environment and the number of vertebrae was expected to have a closer link to ancestry. The first chapter investigates the drivers behind Acontias head shape evolution using geometric morphometric techniques. We found that environmental pressures did affect the evolution of head shape especially in the “soil” and “biome” categories but further investigation is advised. The second chapter explores the viability of using vertebral counts as a novel method for species and/or clade delineation in Acontias and to determine whether vertebral number can be linked to the environment. Delineating species based on vertebral count is likely not an option, however, delineating clades proved to show promising results. A link between vertebral count and environment was found in Acontias with larger bodied species occurring in different environments to smaller body species. In conclusion, the genus Acontias is difficult to delineate morphologically. Genetic sequence analyses can indicate differences and delineate the species. Even though there were differences in morphology based on environmental factors, it is not sufficient to delineate this subfamily alone. Further research is advised and this dissertation provides a good basis to work with. , Thesis (MSc) -- Faculty of Science, Zoology and Entomology, 2021
- Full Text:
- Date Issued: 2021-10
- Authors: Evlambiou, Anthony Andreas
- Date: 2021-10
- Subjects: Skinks South Africa , Acontias South Africa , Typhlosaurus South Africa , Acontias Morphology , Acontias Phylogeny , Acontias Evolution , Vertebrae , Skull Growth , Evolutionary developmental biology
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10962/190690 , vital:45018
- Description: Environmental factors and/or processes can produce differences in general shape between individuals or particular parts of individuals. Examples of these biological processes may include ontogenetic development, adaptation to local geographic factors, or long-term evolutionary diversification. An organism is not likely to be able to optimise a single structure for multiple purposes and so trade-offs are likely to occur. An example of such a structure is the cranium, as it can be used for multiple activities such as defensive and sexual behaviour, locomotion, prey capture, and ingestion. Morphological characteristics have historically been used in the description of species. Genetic analyses have gained popularity as species delineation techniques and have been particularly useful in identifying cryptic species, especially among morphological conserved species like legless skinks of the subfamily Acontinae (e.g. Acontias Cuvier, 1817 and Typhlosaurus Weigmann, 1834). However, completely doing away with morphological techniques during species descriptions is not the best option. Therefore, novel methods to identify species, especially those with similar body plans, are needed. In this dissertation, we explore the links between head shape and vertebral number to environmental pressures to determine whether the evolutionary process is driven by environmental pressures (soil or biome) or is retained through ancestry. A novel species/clade delineation linked to vertebral number is also investigated. Head shape was expected to have a close link to the environment and the number of vertebrae was expected to have a closer link to ancestry. The first chapter investigates the drivers behind Acontias head shape evolution using geometric morphometric techniques. We found that environmental pressures did affect the evolution of head shape especially in the “soil” and “biome” categories but further investigation is advised. The second chapter explores the viability of using vertebral counts as a novel method for species and/or clade delineation in Acontias and to determine whether vertebral number can be linked to the environment. Delineating species based on vertebral count is likely not an option, however, delineating clades proved to show promising results. A link between vertebral count and environment was found in Acontias with larger bodied species occurring in different environments to smaller body species. In conclusion, the genus Acontias is difficult to delineate morphologically. Genetic sequence analyses can indicate differences and delineate the species. Even though there were differences in morphology based on environmental factors, it is not sufficient to delineate this subfamily alone. Further research is advised and this dissertation provides a good basis to work with. , Thesis (MSc) -- Faculty of Science, Zoology and Entomology, 2021
- Full Text:
- Date Issued: 2021-10
Main thesis title 2021: Evaluating the incentive to move freight distribution from road to rail
- Authors: Williams, John Steven
- Date: 2021-04
- Subjects: Gqeberha (South Africa) , Eastern Cape (South Africa) , South Africa
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10948/52953 , vital:44909
- Description: South Africa’s uncompetitive freight logistics system is severely hampering the country’s competitiveness and the current disproportionate reliance on the road freight sector is a main contributing factor. The need for a modal shift from road to rail has long been advocated as a necessity to correct this freight logistics imbalance. This study aims to gain a better understanding of the incentives needed to move freight distribution from road to rail within shorter distance corridors and specifically the Port Elizabeth- Gauteng corridor. Specifically, it evaluates the incentives needed, the importance of cost, distance and whether special capabilities are required to achieve such a move. Empirical data were collected with an online survey and distributed via the Road freight Association (RFA) to transport operators and micro operators within South Africa. Statistical analysis was used to analyse the main research and sub-questions through descriptive statistics, multiple regression analysis and Pearson correlation. The results showed that a mostly strong positive correlation exists between the measured variables in this study while also indicating a significant relationship between the independent variables and moving freight distribution from road to rail. These results proved that all the factors are related to each other and that implementing a move of freight from road to rail would need to include the consideration of all these factors. The study concludes that moving freight distribution from road to rail will be possible if incentives regarding cost rebates or subsidies amongst others are taken into account and included in additional future legislation or more practical implementation plans. , Thesis (MBA) -- Faculty of Business and Economic Sciencence, NMU Business School, 2021
- Full Text: false
- Date Issued: 2021-04
- Authors: Williams, John Steven
- Date: 2021-04
- Subjects: Gqeberha (South Africa) , Eastern Cape (South Africa) , South Africa
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10948/52953 , vital:44909
- Description: South Africa’s uncompetitive freight logistics system is severely hampering the country’s competitiveness and the current disproportionate reliance on the road freight sector is a main contributing factor. The need for a modal shift from road to rail has long been advocated as a necessity to correct this freight logistics imbalance. This study aims to gain a better understanding of the incentives needed to move freight distribution from road to rail within shorter distance corridors and specifically the Port Elizabeth- Gauteng corridor. Specifically, it evaluates the incentives needed, the importance of cost, distance and whether special capabilities are required to achieve such a move. Empirical data were collected with an online survey and distributed via the Road freight Association (RFA) to transport operators and micro operators within South Africa. Statistical analysis was used to analyse the main research and sub-questions through descriptive statistics, multiple regression analysis and Pearson correlation. The results showed that a mostly strong positive correlation exists between the measured variables in this study while also indicating a significant relationship between the independent variables and moving freight distribution from road to rail. These results proved that all the factors are related to each other and that implementing a move of freight from road to rail would need to include the consideration of all these factors. The study concludes that moving freight distribution from road to rail will be possible if incentives regarding cost rebates or subsidies amongst others are taken into account and included in additional future legislation or more practical implementation plans. , Thesis (MBA) -- Faculty of Business and Economic Sciencence, NMU Business School, 2021
- Full Text: false
- Date Issued: 2021-04
Geological study and economic evaluation of the Paardeplaats Coal Exploration Project
- Authors: Gcayi, Gcobani
- Date: 2017
- Subjects: Coal Geology South Africa Mpumalanga , Coal Prospecting South Africa Mpumalanga , Coal mines and mining South Africa Mpumalanga , Geology, Economic South Africa , Coal reserves South Africa Mpumalanga
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10962/59183 , vital:27452
- Description: For a coal mining company the coal resources are an important asset, and they are acquired in a number of different ways, such as obtaining a prospecting permit from government or an existing permit from another entity and or purchasing an operating colliery from another entity. The Paardeplaats Project is a brownfields project located approximately 7 km south west of the town of Belfast in Mpumalanga Province, South Africa, on the far eastern edge of the Witbank Coalfield. The project is located adjacent to an operating mine, Glisa Colliery, owned by Eyesizwe Coal. Eyesizwe Coal was awarded the prospecting permit in 2006 by the Department of Mineral Resources. Subsequent exploration activities, which included airborne magnetic survey and borehole drilling, were conducted between 2008 and 2010. The results of the drilling confirmed the presence of coal resources, which are classified in the Measured, Indicated and Inferred categories. Mining and beneficiation methods from the adjacent Glisa Colliery, which has similar geology to the project area, were assumed in order to generate a coal reserve statement. The Coal Reserve qualities are suitable to the domestic market, particularly Eskom. South Africa’s coal supply is demand driven, primarily from Eskom for electricity generation followed by the export market and thirdly by Sasol for synthetic fuel generation. The majority of Eskom’s existing coal-fired power stations are located in the Mpumalanga Province, which provides a viable market for coal projects in Mpumalanga when considering existing transport infrastructure and transportation costs. Eskom’s continued demand for coal in the Mpumalanga region, at least until 2040, provides a future market for advanced coal projects in the region. A valuation of the project using the Cash Flow Approach showed the project to be economically viable. , Thesis (MSc) -- Faculty of Faculty of Science, Geology, 2017
- Full Text:
- Date Issued: 2017
- Authors: Gcayi, Gcobani
- Date: 2017
- Subjects: Coal Geology South Africa Mpumalanga , Coal Prospecting South Africa Mpumalanga , Coal mines and mining South Africa Mpumalanga , Geology, Economic South Africa , Coal reserves South Africa Mpumalanga
- Language: English
- Type: Master's theses , text
- Identifier: http://hdl.handle.net/10962/59183 , vital:27452
- Description: For a coal mining company the coal resources are an important asset, and they are acquired in a number of different ways, such as obtaining a prospecting permit from government or an existing permit from another entity and or purchasing an operating colliery from another entity. The Paardeplaats Project is a brownfields project located approximately 7 km south west of the town of Belfast in Mpumalanga Province, South Africa, on the far eastern edge of the Witbank Coalfield. The project is located adjacent to an operating mine, Glisa Colliery, owned by Eyesizwe Coal. Eyesizwe Coal was awarded the prospecting permit in 2006 by the Department of Mineral Resources. Subsequent exploration activities, which included airborne magnetic survey and borehole drilling, were conducted between 2008 and 2010. The results of the drilling confirmed the presence of coal resources, which are classified in the Measured, Indicated and Inferred categories. Mining and beneficiation methods from the adjacent Glisa Colliery, which has similar geology to the project area, were assumed in order to generate a coal reserve statement. The Coal Reserve qualities are suitable to the domestic market, particularly Eskom. South Africa’s coal supply is demand driven, primarily from Eskom for electricity generation followed by the export market and thirdly by Sasol for synthetic fuel generation. The majority of Eskom’s existing coal-fired power stations are located in the Mpumalanga Province, which provides a viable market for coal projects in Mpumalanga when considering existing transport infrastructure and transportation costs. Eskom’s continued demand for coal in the Mpumalanga region, at least until 2040, provides a future market for advanced coal projects in the region. A valuation of the project using the Cash Flow Approach showed the project to be economically viable. , Thesis (MSc) -- Faculty of Faculty of Science, Geology, 2017
- Full Text:
- Date Issued: 2017
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