An investigation into the school experiences of HIV-positive secondary school learners on ARV treatment in Katutura, Windhoek
- Authors: Haipinge, Emilie
- Date: 2013
- Subjects: HIV-positive youth -- Namibia -- Katutura (Windhoek) HIV-positive youth -- Social conditions -- Namibia -- Katutura (Windhoek) HIV infections -- Social aspects -- Namibia -- Katutura (Windhoek) HIV infections -- Psychological aspects -- Namibia -- Katutura (Windhoek) AIDS phobia -- Namibia -- Katutura (Windhoek) Antiretroviral agents
- Language: English
- Type: Thesis , Masters , MEd
- Identifier: vital:1837 , http://hdl.handle.net/10962/d1004334
- Description: What are the school experiences of HIV-positive secondary school learners on ARV treatment? Although the provision of life-saving antiretroviral (ARV) treatment is central in the medical and policy response to the HIV pandemic, relatively little research (in the SADC region and in Namibia particularly) attends to people’s experiences and the social effects of taking ARV treatment. This study probed the experiences of high school learners on ARV treatment in Khomas Region, Namibia. As researcher I used a qualitative case study design based mainly on interviews with a purposive, select sample of eight learners at the school where I am a teacher-counsellor. Methods used also included: observations; focus group interviews with eight teachers at the site school; a questionnaire survey with Life Skills teachers from 25 schools in the Khomas Region; and document analysis. Using a theory of health-related stigma and discrimination as well as perspectives on resilience and agency as conceptual and analytical lenses, this study found that only a handful of these learners were living openly with HIV and AIDS. Being both HIV-positive and on ARV medication was a double bind for learners facing pervasive stigma and discrimination in and out of school. Discourses associated with HIV and AIDS, sex, and sexuality shaped people’s response to them and they feared being ‘caught out’. Here the study explores the complex reciprocal relationship between cause and effect in stigma, showing some consequences for these learners: isolation (both voluntary and imposed), mental anguish, depression and suicidal leanings; also (at school) absenteeism, grade repetition and dropout. Distinguishing stigma from discrimination in this study enabled insight into actual practices that constrain learner participation and inclusion in and out of school. Trust between learners on ARVs and teachers proved to be low. Teacher respondents not only felt unequipped to deal with the psychosocial needs of learners on ARVs but also indicated that confronting these needs animated their personal vulnerability (around HIV-related experiences in their own families). However, hopeful patterns also emerged. Some mediatory factors out of school shaped these learners’ experiences and identities positively, with implications for in-school experiences and participation. Some learner journeys reflected shifts from deep despair towards the emergence of voice, positive self-concepts and resilient dispositions. Here, also, this study enters a neglected area of research, showing how the complex interplay of learners’ own agency with social support brought these positive outcomes. Most learners had experienced rejection from immediate family, receiving support rather from community members who became ‘family’. The study thus also raises pressing questions on the nature of support structures (both in and out of school) in contexts shaped by HIV and AIDS, where stigma and discrimination are pervasive and where stable family structures, parental oversight and ‘normal’ progression through school cannot be assumed. It recommends that schools gain better insight into how learners’ circumstances shape their experiences, and develop internal policies, procedures and networks to reduce stigma and discrimination against HIV-positive learners on ARV treatment, as well as. ensuring material, medical, emotional, and psychological support for them.
- Full Text:
- Date Issued: 2013
- Authors: Haipinge, Emilie
- Date: 2013
- Subjects: HIV-positive youth -- Namibia -- Katutura (Windhoek) HIV-positive youth -- Social conditions -- Namibia -- Katutura (Windhoek) HIV infections -- Social aspects -- Namibia -- Katutura (Windhoek) HIV infections -- Psychological aspects -- Namibia -- Katutura (Windhoek) AIDS phobia -- Namibia -- Katutura (Windhoek) Antiretroviral agents
- Language: English
- Type: Thesis , Masters , MEd
- Identifier: vital:1837 , http://hdl.handle.net/10962/d1004334
- Description: What are the school experiences of HIV-positive secondary school learners on ARV treatment? Although the provision of life-saving antiretroviral (ARV) treatment is central in the medical and policy response to the HIV pandemic, relatively little research (in the SADC region and in Namibia particularly) attends to people’s experiences and the social effects of taking ARV treatment. This study probed the experiences of high school learners on ARV treatment in Khomas Region, Namibia. As researcher I used a qualitative case study design based mainly on interviews with a purposive, select sample of eight learners at the school where I am a teacher-counsellor. Methods used also included: observations; focus group interviews with eight teachers at the site school; a questionnaire survey with Life Skills teachers from 25 schools in the Khomas Region; and document analysis. Using a theory of health-related stigma and discrimination as well as perspectives on resilience and agency as conceptual and analytical lenses, this study found that only a handful of these learners were living openly with HIV and AIDS. Being both HIV-positive and on ARV medication was a double bind for learners facing pervasive stigma and discrimination in and out of school. Discourses associated with HIV and AIDS, sex, and sexuality shaped people’s response to them and they feared being ‘caught out’. Here the study explores the complex reciprocal relationship between cause and effect in stigma, showing some consequences for these learners: isolation (both voluntary and imposed), mental anguish, depression and suicidal leanings; also (at school) absenteeism, grade repetition and dropout. Distinguishing stigma from discrimination in this study enabled insight into actual practices that constrain learner participation and inclusion in and out of school. Trust between learners on ARVs and teachers proved to be low. Teacher respondents not only felt unequipped to deal with the psychosocial needs of learners on ARVs but also indicated that confronting these needs animated their personal vulnerability (around HIV-related experiences in their own families). However, hopeful patterns also emerged. Some mediatory factors out of school shaped these learners’ experiences and identities positively, with implications for in-school experiences and participation. Some learner journeys reflected shifts from deep despair towards the emergence of voice, positive self-concepts and resilient dispositions. Here, also, this study enters a neglected area of research, showing how the complex interplay of learners’ own agency with social support brought these positive outcomes. Most learners had experienced rejection from immediate family, receiving support rather from community members who became ‘family’. The study thus also raises pressing questions on the nature of support structures (both in and out of school) in contexts shaped by HIV and AIDS, where stigma and discrimination are pervasive and where stable family structures, parental oversight and ‘normal’ progression through school cannot be assumed. It recommends that schools gain better insight into how learners’ circumstances shape their experiences, and develop internal policies, procedures and networks to reduce stigma and discrimination against HIV-positive learners on ARV treatment, as well as. ensuring material, medical, emotional, and psychological support for them.
- Full Text:
- Date Issued: 2013
GIS in participatory catchment management : a case study in the Kat River Valley, Eastern Cape, South Africa
- Authors: McMaster, Alistair
- Date: 2002 , 2013-05-16
- Subjects: Watershed management -- South Africa -- Eastern Cape , Geographic information systems
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: vital:4868 , http://hdl.handle.net/10962/d1007602 , Watershed management -- South Africa -- Eastern Cape , Geographic information systems
- Description: In water resources management in South Africa, there is an emphasis on public participation. On a river catchment basis, one of the mechanisms for such participation is the establishment of catchment forums. However, members of catchment forums, particularly those coming from poor or rural communities, cannot be expected to engage in catchment management without having been enabled to do so. This thesis considers the use of GIS in the process of enabling the Kat River Valley Catchment Forum to better participate in catchment management. The research focus is on the use of GIS to facilitate an understanding of the Kat River Catchment and associated catchment concepts, and constructive communication and sharing, among the Catchment Forum. The GIS is used in the context of "GIS for Participatory Research", an outgrowth of Public Participation GIS (PPGIS), which focuses on GIS as a tool for empowerment within participatory processes. The study has used Action Research, situated in the Critical paradigm, as a methodology. The research has included seven Forum workshop processes and one series of in-village meetings. These engagements have involved map-based appraisals, issues and resource mapping, map-based planning, and the use of on-screen GIS for presentation and sharing. The use of GIS has facilitated the creation of customised maps, the integration of village-scale mapping into a catchment scale product, the presentation of synthesised data in digital and hardcopy format and, in so doing, has allowed catchment-scale appraisal. Outcomes enabling participation in catchment management have included developed mapping skills and an enhanced understanding of the catchment as a whole, and developed conceptual access to a decision-making language (or way of thinking), among participants. Furthermore, the Forum as a whole has identified common needs, and has developed a set of map-based action plans. The research process has yielded a number of lessons regarding "GIS for participation" and the participatory framework within which it takes place. Chief among these is that the GIS operator should take on the role of a participatory practitioner.
- Full Text:
- Date Issued: 2002
- Authors: McMaster, Alistair
- Date: 2002 , 2013-05-16
- Subjects: Watershed management -- South Africa -- Eastern Cape , Geographic information systems
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: vital:4868 , http://hdl.handle.net/10962/d1007602 , Watershed management -- South Africa -- Eastern Cape , Geographic information systems
- Description: In water resources management in South Africa, there is an emphasis on public participation. On a river catchment basis, one of the mechanisms for such participation is the establishment of catchment forums. However, members of catchment forums, particularly those coming from poor or rural communities, cannot be expected to engage in catchment management without having been enabled to do so. This thesis considers the use of GIS in the process of enabling the Kat River Valley Catchment Forum to better participate in catchment management. The research focus is on the use of GIS to facilitate an understanding of the Kat River Catchment and associated catchment concepts, and constructive communication and sharing, among the Catchment Forum. The GIS is used in the context of "GIS for Participatory Research", an outgrowth of Public Participation GIS (PPGIS), which focuses on GIS as a tool for empowerment within participatory processes. The study has used Action Research, situated in the Critical paradigm, as a methodology. The research has included seven Forum workshop processes and one series of in-village meetings. These engagements have involved map-based appraisals, issues and resource mapping, map-based planning, and the use of on-screen GIS for presentation and sharing. The use of GIS has facilitated the creation of customised maps, the integration of village-scale mapping into a catchment scale product, the presentation of synthesised data in digital and hardcopy format and, in so doing, has allowed catchment-scale appraisal. Outcomes enabling participation in catchment management have included developed mapping skills and an enhanced understanding of the catchment as a whole, and developed conceptual access to a decision-making language (or way of thinking), among participants. Furthermore, the Forum as a whole has identified common needs, and has developed a set of map-based action plans. The research process has yielded a number of lessons regarding "GIS for participation" and the participatory framework within which it takes place. Chief among these is that the GIS operator should take on the role of a participatory practitioner.
- Full Text:
- Date Issued: 2002
An investigation into the antioxidative potential and regulatory aspects of liver tryptophan 2,3-dioxygenase by tryptophan and related analogues
- Authors: Antunes, Ana Paula Martins
- Date: 1998
- Subjects: Tryptophan -- Physiological effect , Antioxidants , Liver
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: vital:4010 , http://hdl.handle.net/10962/d1004070 , Tryptophan -- Physiological effect , Antioxidants , Liver
- Description: The amino acid, tryptophan, obtained through dietary means, is metabolised by the enzymes tryptophan 2,3-dioxygenase (TDO), indoleamine 2,3-dioxygenase (IDO) and tryptophan hydroxylase. All the enzymes have an effect on circulating tryptophan levels, especially TDO, since it is the major site of tryptophan catabolism in the liver and results in the production of kynurenine metabolites, viz. kynurenine, kynurenic acid, 3-hydroxyanthranilic acid and quinolinic acid. Extrahepatically, IDO is responsible for the synthesis of the kynurenine metabolites. Tryptophan 2,3-dioxygenase and IDO activity is increased by hormones or substrates such as tryptophan, and inflammation, in the case of IDO. Tryptophan availability for serotonin (5-HT) synthesis by the enzyme tryptophan hydroxylase is primarily dependent on TDO activity. A study was attempted in order to ascertain whether any of the endogenous metabolites of the kynurenine and serotonergic pathways would be able to inhibit TDO activity. Results showed that although the kynurenines had no effect, the indoleamines, except for the indoleacetic acids, were able to reduce TDO activity. 6-Methoxy-2-benzoxazolinone (6-MBOA), a structural analogue to melatonin, was the most potent inhibitor with a reduction in activity of 55 % compared with the control. The pineal gland in the rat brain has been shown to have the highest IDO activity. With induction, the kynurenine metabolite concentrations of kynurenic acid and quinolinic acid are increased. The effects of both compounds were determined on the serotonergic pathway. Although kynurenic acid produced no significant effect, quinolinic acid significantly reduced N-acetylserotonin and melatonin synthesis at concentrations of lOJLM and 100 JLM respectively. Many authors have implicated oxygen derived species as causative agents in the important neurodegenerative disorders such as Parkinson's and Huntington's disease. Increased radical generation and lipid peroxidation have been suggested to be responsible for the toxic destruction of neurons, especially in the brain because of its high lipid content and oxygen demand. The brain is therefore vulnerable to oxidative attack. During inflammatory diseases, IDO is induced with a resultant increase in kynurenines. This study was also an attempt at determining the effect of kynurenines on lipid peroxidation. All metabolites of the kynurenine pathway were able to induce lipid peroxidation significantly. The antioxidative potential of various tryptophan analogues, viz. serotonin, melatonin and 6-methoxy-2-benzoxazolinone, was determined using quinolinic acid-induced lipid peroxidation. Serotonin, melatonin and 6-MBOA were able to significantly reduce quinolinic acid-induced lipid peroxidation.
- Full Text:
- Date Issued: 1998
- Authors: Antunes, Ana Paula Martins
- Date: 1998
- Subjects: Tryptophan -- Physiological effect , Antioxidants , Liver
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: vital:4010 , http://hdl.handle.net/10962/d1004070 , Tryptophan -- Physiological effect , Antioxidants , Liver
- Description: The amino acid, tryptophan, obtained through dietary means, is metabolised by the enzymes tryptophan 2,3-dioxygenase (TDO), indoleamine 2,3-dioxygenase (IDO) and tryptophan hydroxylase. All the enzymes have an effect on circulating tryptophan levels, especially TDO, since it is the major site of tryptophan catabolism in the liver and results in the production of kynurenine metabolites, viz. kynurenine, kynurenic acid, 3-hydroxyanthranilic acid and quinolinic acid. Extrahepatically, IDO is responsible for the synthesis of the kynurenine metabolites. Tryptophan 2,3-dioxygenase and IDO activity is increased by hormones or substrates such as tryptophan, and inflammation, in the case of IDO. Tryptophan availability for serotonin (5-HT) synthesis by the enzyme tryptophan hydroxylase is primarily dependent on TDO activity. A study was attempted in order to ascertain whether any of the endogenous metabolites of the kynurenine and serotonergic pathways would be able to inhibit TDO activity. Results showed that although the kynurenines had no effect, the indoleamines, except for the indoleacetic acids, were able to reduce TDO activity. 6-Methoxy-2-benzoxazolinone (6-MBOA), a structural analogue to melatonin, was the most potent inhibitor with a reduction in activity of 55 % compared with the control. The pineal gland in the rat brain has been shown to have the highest IDO activity. With induction, the kynurenine metabolite concentrations of kynurenic acid and quinolinic acid are increased. The effects of both compounds were determined on the serotonergic pathway. Although kynurenic acid produced no significant effect, quinolinic acid significantly reduced N-acetylserotonin and melatonin synthesis at concentrations of lOJLM and 100 JLM respectively. Many authors have implicated oxygen derived species as causative agents in the important neurodegenerative disorders such as Parkinson's and Huntington's disease. Increased radical generation and lipid peroxidation have been suggested to be responsible for the toxic destruction of neurons, especially in the brain because of its high lipid content and oxygen demand. The brain is therefore vulnerable to oxidative attack. During inflammatory diseases, IDO is induced with a resultant increase in kynurenines. This study was also an attempt at determining the effect of kynurenines on lipid peroxidation. All metabolites of the kynurenine pathway were able to induce lipid peroxidation significantly. The antioxidative potential of various tryptophan analogues, viz. serotonin, melatonin and 6-methoxy-2-benzoxazolinone, was determined using quinolinic acid-induced lipid peroxidation. Serotonin, melatonin and 6-MBOA were able to significantly reduce quinolinic acid-induced lipid peroxidation.
- Full Text:
- Date Issued: 1998
An investigation into some critical computer networking parameters : Internet addressing and routing
- Authors: Isted, Edwin David
- Date: 1996
- Subjects: Computer networks , Internet , Electronic mail systems
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: vital:4608 , http://hdl.handle.net/10962/d1004874 , Computer networks , Internet , Electronic mail systems
- Description: This thesis describes the evaluation of several proposals suggested as replacements for the currenT Internet's TCPJIP protocol suite. The emphasis of this thesis is on how the proposals solve the current routing and addressing problems associated with the Internet. The addressing problem is found to be related to address space depletion, and the routing problem related to excessive routing costs. The evaluation is performed based on criteria selected for their applicability as future Internet design criteria. AIl the protocols are evaluated using the above-mentioned criteria. It is concluded that the most suitable addressing mechanism is an expandable multi-level format, with a logical separation of location and host identification information. Similarly, the most suitable network representation technique is found to be an unrestricted hierarchical structure which uses a suitable abstraction mechanism. It is further found that these two solutions could adequately solve the existing addressing and routing problems and allow substantial growth of the Internet.
- Full Text:
- Date Issued: 1996
An investigation into some critical computer networking parameters : Internet addressing and routing
- Authors: Isted, Edwin David
- Date: 1996
- Subjects: Computer networks , Internet , Electronic mail systems
- Language: English
- Type: Thesis , Masters , MSc
- Identifier: vital:4608 , http://hdl.handle.net/10962/d1004874 , Computer networks , Internet , Electronic mail systems
- Description: This thesis describes the evaluation of several proposals suggested as replacements for the currenT Internet's TCPJIP protocol suite. The emphasis of this thesis is on how the proposals solve the current routing and addressing problems associated with the Internet. The addressing problem is found to be related to address space depletion, and the routing problem related to excessive routing costs. The evaluation is performed based on criteria selected for their applicability as future Internet design criteria. AIl the protocols are evaluated using the above-mentioned criteria. It is concluded that the most suitable addressing mechanism is an expandable multi-level format, with a logical separation of location and host identification information. Similarly, the most suitable network representation technique is found to be an unrestricted hierarchical structure which uses a suitable abstraction mechanism. It is further found that these two solutions could adequately solve the existing addressing and routing problems and allow substantial growth of the Internet.
- Full Text:
- Date Issued: 1996
The evolution of the working conditions and associated legislation of apprentices and child labour in British factories and trades from the late 18th to the middle of the 19th centuries
- Authors: Heaton, James R.
- Date: 1977
- Subjects: Labor -- Great Britain -- History -- 18th century , Labor -- Great Britain -- History -- 19th century , Working class -- Great Britain -- History -- 18th century , Working class -- Great Britain -- History -- 19th century , Child labor -- Great Britain , Labor laws and legislation -- Great Britain -- History , Factories -- Great Britain -- Employees
- Language: English
- Type: Thesis , Masters , MA
- Identifier: vital:1089 , http://hdl.handle.net/10962/d1012242 , Labor -- Great Britain -- History -- 18th century , Labor -- Great Britain -- History -- 19th century , Working class -- Great Britain -- History -- 18th century , Working class -- Great Britain -- History -- 19th century , Child labor -- Great Britain , Labor laws and legislation -- Great Britain -- History , Factories -- Great Britain -- Employees
- Description: Both modern and contemporary commentators have over the past 140 years written many millions of words on the subject of the abuse of child labour in factories and trades in the first half of the nineteenth century. The subject was highly charged with emotion at that time. The detailed observations of intelligent and perceptive men contrast with the partial accounts of honest and not so honest early Victorians. Together they have blurred the definition between truth and the embellishment of it. This lack of clarity on the issue of child labour has left modern historians great scope for widely differing interpretations and the evidence for believing that conditions were as bad or as good as suited their particular point of view. It is regretted that there is insufficient material in South Africa to enter fully into the often bitter arguments of the, so called, 'optimists' and 'pessimists' in respect of the improvement or deterioration of the standard of living of the labouring classes in the first half of the nineteenth century. Child labour was not one of the inventions of the Industrial Revolution. The labour of children within the domestic economy had, certainly from the seventeenth and eighteenth centuries, been regarded as socially acceptable. The aim of this work is to trace the conditions of child labour in the early years of the Industrial Revolution as the spread of factories demanded more and more young hands and imposed an alien and sometimes inhuman discipline on the workers. As the numbers of children employed expanded not only in total but also as a proportion of the total labour force, the realisation that the labour of children was presenting a grave social problem gradually dawned upon the governments of the time. This work traces the development of legislation from the first faltering step forward of the Health and Morals of Apprentices Act of 1802 to the passing of the Factory Act of 1847 which provided for a ten hours' working day. This type of legislation was an experiment which developed in efficiency by trial and error. Detailed consideration is given to the arguments of the supporters and the opponents of restrictions being placed on the complete freedom of the manufacturers. This was a battle eventually to be won by the supporters of restriction on the freedom of the masters. Nearly twenty years have passed since detail ed consideration was given to the parallel development of the awareness that the labour of children was a problem and the steps taken to alleviate it. The aim in this work is to consider the most recent publications that deal with particular aspects of the problem. The intention is to penetrate the contradictory claims made in the first half of the nineteenth century, and to attempt to clarify as accurately as possible the realities of the conditions of child labour and to trace their improvement to the middle of the century.
- Full Text:
- Date Issued: 1977
- Authors: Heaton, James R.
- Date: 1977
- Subjects: Labor -- Great Britain -- History -- 18th century , Labor -- Great Britain -- History -- 19th century , Working class -- Great Britain -- History -- 18th century , Working class -- Great Britain -- History -- 19th century , Child labor -- Great Britain , Labor laws and legislation -- Great Britain -- History , Factories -- Great Britain -- Employees
- Language: English
- Type: Thesis , Masters , MA
- Identifier: vital:1089 , http://hdl.handle.net/10962/d1012242 , Labor -- Great Britain -- History -- 18th century , Labor -- Great Britain -- History -- 19th century , Working class -- Great Britain -- History -- 18th century , Working class -- Great Britain -- History -- 19th century , Child labor -- Great Britain , Labor laws and legislation -- Great Britain -- History , Factories -- Great Britain -- Employees
- Description: Both modern and contemporary commentators have over the past 140 years written many millions of words on the subject of the abuse of child labour in factories and trades in the first half of the nineteenth century. The subject was highly charged with emotion at that time. The detailed observations of intelligent and perceptive men contrast with the partial accounts of honest and not so honest early Victorians. Together they have blurred the definition between truth and the embellishment of it. This lack of clarity on the issue of child labour has left modern historians great scope for widely differing interpretations and the evidence for believing that conditions were as bad or as good as suited their particular point of view. It is regretted that there is insufficient material in South Africa to enter fully into the often bitter arguments of the, so called, 'optimists' and 'pessimists' in respect of the improvement or deterioration of the standard of living of the labouring classes in the first half of the nineteenth century. Child labour was not one of the inventions of the Industrial Revolution. The labour of children within the domestic economy had, certainly from the seventeenth and eighteenth centuries, been regarded as socially acceptable. The aim of this work is to trace the conditions of child labour in the early years of the Industrial Revolution as the spread of factories demanded more and more young hands and imposed an alien and sometimes inhuman discipline on the workers. As the numbers of children employed expanded not only in total but also as a proportion of the total labour force, the realisation that the labour of children was presenting a grave social problem gradually dawned upon the governments of the time. This work traces the development of legislation from the first faltering step forward of the Health and Morals of Apprentices Act of 1802 to the passing of the Factory Act of 1847 which provided for a ten hours' working day. This type of legislation was an experiment which developed in efficiency by trial and error. Detailed consideration is given to the arguments of the supporters and the opponents of restrictions being placed on the complete freedom of the manufacturers. This was a battle eventually to be won by the supporters of restriction on the freedom of the masters. Nearly twenty years have passed since detail ed consideration was given to the parallel development of the awareness that the labour of children was a problem and the steps taken to alleviate it. The aim in this work is to consider the most recent publications that deal with particular aspects of the problem. The intention is to penetrate the contradictory claims made in the first half of the nineteenth century, and to attempt to clarify as accurately as possible the realities of the conditions of child labour and to trace their improvement to the middle of the century.
- Full Text:
- Date Issued: 1977
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