- Title
- Evaluation of Salivary COVID-19 IGG Between Vaccinated and Unvaccinated Individuals in Mthatha
- Creator
- Owusu, William
- Description
- As thousands of individuals around the world battle with life-threatening conditions in intensive care units, millions more are grappling with the enduring and debilitating effects of COVID-19. Despite the availability of effective vaccines, the prevalence of COVID-19 continues to rise, largely due to vaccine hesitancy, which remains a significant obstacle to achieving global immunity against the virus. Vaccine hesitancy stems from a lack of confidence in the safety, efficacy, and accessibility of vaccines, which increases COVID 19 mortality and morbidity rates. Understanding the immune response elicited by vaccination could provide critical insights into the benefits of immunisation and help address vaccine hesitancy. Therefore, this study aims to quantify and compare the salivary IgG levels in individuals vaccinated against SARS-CoV-2 with those who remain unvaccinated, highlighting the immunological advantage of vaccination. A case-control study design was used to conduct this study, using convenience sampling amongst 183 willing individuals aged 18 years and above from the town of Mthatha, O.R Tambo District, Eastern Cape. Participants were recruited from the Mthatha CBD, and their vaccination status was recorded and verified on the government website. Following aseptic protocols, saliva samples were collected in microcentrifuge tubes and stored in a cooler before transfer to the laboratory. The saliva samples were then analysed using the Bio-Plex Pro Human IgG SARS-CoV-2 assay kit, carefully following the instructions provided by the manufacturer…
- Description
- Degree: M. Science (Physiological Sciences)
- Date
- 2022
- Subject
- COVID-19 salivary IgG levels
- Subject
- Vaccine hesitancy
- Subject
- SARS-CoV-2
- Subject
- Immunological advantages of vaccination
- Subject
- Mthatha
- Type
- Masters (Thesis)
- Identifier
- http://hdl.handle.net/11260/13528
- Identifier
- vital:78943
- Language
- English
- Rights
- Walter Sisulu University
- Hits: 11
- Visitors: 10
- Downloads: 3
| Thumbnail | File | Description | Size | Format | |||
|---|---|---|---|---|---|---|---|
| View Details | SOURCE1 | Owusu, W. Masters Thesis.pdf | 1 MB | Adobe Acrobat PDF | View Details |